Cov lus qhia
| Zog: | Off-dawb lossis dawb amorphous hmoov |
| Purity (HPLC): | 98% min |
| Purity (los ntawm 31p NMR): | 98% min |
| Tus kheej (los ntawm 1H NMR): | Txhawm rau ua raws cov qauv |
| Residual cov kuab tshuaj: | 3.0% Max |
| Dej: | 0.5% max |
| Solubility Clarity: | 0.2 m kev daws teeb meem hauv acetonitrile yog pub dawb los ntawm tsis muaj kev cuam tshuam |
Cov Ntawv Thov
1. Khoom cua ntawm hloov RNA oligonucleides
Siv hauv cov khoom siv-theem tshuaj synthesis kom sib xyaw ua ke 2'-o-methylizytidine nrog kev tiv thaiv n4-acetyl.
Ua rau kev tsim kho kom zoo ntawm RNA alolecules muaj ntuj los yog tsim cov kev hloov kho epitransectomic hloov kho.
2. RNA kho thiab txhaj tshuaj tiv thaiv kab mob
Qhov tseem ceeb rau kev ua tau hloov kho cov lwg me me (piv txwv li, cov tshuaj tiv thaiv OligonucleSides, MRNA ruaj khov dua thiab tsis muaj zog tiv thaiv).
2'-o-methyl thiab n4-acetyl hloov kho kom txhim kho Nuclease tsis kam thiab txo lub zog tiv thaiv kev tiv thaiv.
3. EpitransCRAcriptomics
Tso cai rau kev kawm txog yuav ua li cas Cytidine kev hloov kho cuam tshuam RNA qauv, muaj nuj nqi, thiab kev cuam tshuam.
Pab tshaj tawm cov kab ke roj ntsha ntawm n4-acetylation thiab 2'-o-methylation hauv kev ua rog RNA thiab cov thawj tswj cov noob.
4. Molecular biology thiab biochemistry
Siv nyob rau hauv enzyme xav pom los txheeb xyuas methyltransferte thiab acetyltransferase cov haujlwm.
Kev tshawb nrhiav qhov kev tshawb nrhiav ntawm RNN-protein kev sib cuam tshuam thiab RNA ruaj khov meticial.
Cov txiaj ntsig
Txhim Kho RNA stability:Kev sib txuam ntawm 2'-o-methyl thiab n4-acetyl pawg txhim kho RNA yuav tsis taus rau kev ua tsis taus.
Txo immunogenicity:Kho cov nucleosides txo cov tshuaj tiv thaiv kab mob ntawm cov hluavtaws RNAttectics.
High synthesis txuag:Cov pab pawg tiv thaiv kom muaj tseeb thiab muaj txiaj ntsig tau zoo thaum lub sijhawm Synthesis.
Kev Tshawb Fawb Txog Kev Tshawb Fawb:Pab kom cov ncauj lus kom ntxaws ntawm RNA kev hloov kho thiab lawv cov roj ntsha roj ntsha.
Tag
5-O-DMT-2-O-Me-Kuv-RC (CASSCA (CASE TSAV TAU DERIVCY TIV THAIV DEV Nws ua rau muaj kev cuam tshuam ntawm kev siv hluav taws xob cuam tshuam nrog RNIGONUCLETICS siv hauv RNAtectSuics, EpitransCROTOMICS, thiab Molecular Biology. Qhov no reagent facilitates kev tsim cov ruaj khov, ua haujlwm, thiab tsawg dua immunogenic RNA cov ntawv thov hauv cov kev siv ntau yam hauv Biotechnology thiab Tshuaj Txiaj.
Cim npe nrov: 5-O-DMT-2-O-Me-RC (N-AC) -3-CEDPA 丨
