Cov lus qhia
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Kev piav txog |
Dawb rau me ntsis daj hmoov |
|
Purity los ntawm hplc |
99. {0}% min |
|
So |
Cov tshuaj tsis muaj kob rau plaub hau daj |
|
Daim qhia npe |
Lub Hnmr Spectrum conforms rau kev teeb tsa |
Cov Ntawv Thovntawm xanthine 丨 cas 69-89-6
1. Biochemical thiab Tshawb Nrhiav Kho Mob
Tus tseem ceeb Intermediate hauv Purine Metabolism, pab li aPROMSTOR RAU uric acid.
Siv nyob rau hauvenzyme ciathiabKev Kawm MetabolicTxhawm rau tshawb xyuas:
Purine Defradation
Enzyme ua si (piv txwv li, xanthine oxidase thiab xanthine dehydrogenase)
Kev tsis sib haumgout, xanthinuria, thiabsiab phem
2. Kev Tshawb Nrhiav Tshuaj
Ze ze rauMethylxanthines(piv txwv li, caffeine, mobromine, theophylline), ua rau nws aPib TawHauv synthesis ntawm:
Tus tub pob txha
Txhawb nqa
Cua vasodilators
Kawm rau nws lub luag haujlwm hauvAdenosine receptor kev hloov kho, uas cuam tshuam rau cov kab mob plawv thiab nruab nrab ntawm lub cev ua haujlwm.
3. Antioxidant thiab Dawb radical Kev Tshawb Fawb
Raws li ib substrate rauxanthine oxidase, nws yog siv nyob rau hauv kev tsimreactive oxygen hom (Ros)hauv kev sim qauv.
Pab ntsuasAntioxidant Caphabiliesntawm ntau yam sib xyaw hauvnyob rau hauv vitro oxidative kev ruaj ntseg nqis.
4. Kev tshuaj ntsuam reagent
Ua haujlwm hauvKev ua haujlwm siab ua kua chromatography (HPLC)thiabspectrophotometrymus kawm purine metabolism.
Siv raws li aKev Siv Cov Compoundrau kev kuaj xyuas purine hauv paus hauv nucleic acid tsom xam.
5. Tshuaj tsim qauv thiab kev txhim kho
Ua hauj lwmScaffold MoleculeRau cov khoom siv hluavtaws analogs hom:
Adenosine receptors (A1, A2A, A3B, A3)
Phosphodiesterase enzymes (pdes)
Kinease inibitors
Pab tsimBioctive derivativesnrog cov ntawv thov hauvCns kev tsis sib haum xeeb, mob hawb pob, thiab kab mob plawv.
Cov txiaj ntsig
1. Kev txheeb xyuas kev lom zem
Xanthine 丨 cas 69-89-6} muaj tshwm sim hauv lubmetabolic tawg ntawm purineshauv tib neeg thiab tsiaj.
Plays ib lub luag haujlwm tseem ceeb hauv kev nkag siab cov kabmob cuam tshuam nrogPurine metabolism tsis sib xws, xws li:
Gout
Renal lithiasis
Lesch-nyhan syndrome
2. Kev Tshawb Xyuas Kev Tshawb Xyuas
Yooj yim incorporated rau hauvenzymatic cov tshuaj tiv thaivTxhawm rau kawm oxidative kev ntxhov siab thiab antioxidant thaj chaw.
Nws kev hloov pauv los ntawm Xanthine Oxidase ua rau nws muaj txiaj ntsig hauvRos Generation Kev Kawm, simulatingKev Mob Siab.
3. Khoom siv hluavtaws yooj yim
Ua li ibprecursor lossis nruab nrabHauv kev tsim ntau ntauKws Tshuaj thiab Agnholicical Molecules.
Nws lub nplhaib purine nplhaib muaj cov ntsiab lus hloov kho ntau yam rauSAR (qauv-kev sib raug zoo)Kev tshawb nrhiav.
4. Kev tuav txoj kev nyab xeeb thiab tus nqi qis
Piv rau lwm yam analogs, xanthine yog:
Tsis-lomnyob rau hauv mederate nyiaj
Kev Lag Luam Muajntawm tus nqi qis
Ruaj khov nyob rau hauv tus qauv cia
Tag
Xanthine 丨 cas 69-89-6yog ib qho tseem ceeb rau kev ua kom zoo nkauj los ua haujlwm uas ua rau ob qho tib si ametabolic unflmediat thiab ib qho kev tshawb fawb ntau yamCov. Nws yog qhov tseem ceeb hauv kev tshawb fawb ntawmPurine Metabolism, Oxidative Kev Nyuaj Siab, Enzyme Muaj Luag Haujlwm, thiabKev nrhiav yeeb tshuajCov. Nws cov txheej txheem sib thooj rau cov metylalting biochlxt, thiab sib xyaw nrog kev siv roj ntsha ua nws cov txiaj ntsig zoo hauvBiochemistry, chaw muag tshuaj, thiabKev ntsuas tshuaj anchister.
Cim npe nrov: Xanthine 丨 cas 69-89-6, Tuam Tshoj Xanthine 丨 Li 69-89-6 Cov chaw tsim khoom, cov chaw tsim khoom, Hoobkas
