Cov lus qhia
| Zog: | Tawm-dawb rau cov hmoov dawb dawb |
| Clarity ntawm kev daws: | 0.2m kev daws teeb meem hauv cov acetonitrile yog pub dawb los ntawm tsis muaj qhov cuam tshuam |
| HPLP Purity: | 98% min |
| 31 p nmr purity: | 98% min |
| Dej: | 0.3% max |
| Residual Hnyav: | 3% max |
| Cov khoom siv keeb kwm: | Tsis muaj paub tsiaj txhu cov ntaub ntawv tau siv hauv kev tsim cov khoom no |
Cov Ntawv Thov
1. Khoom cua RNA oligonucleAruction ntau lawm
Siv ntau yam tshuaj lom neeg hluavtaws hluavtaws oligonucleotides, tshwj xeeb yog cov uas muaj 2'-o-methyladenosine hloov kho.
Cov pab pawg tiv thaiv cia cov txheej txheem stepwise ntawm RNA strands nrog kev tswj hwm siab thiab tswj hwm.
Ua rau cov kev tsim cov ntsiab lus hloov pauv ua ntu zus rau kev tshawb fawb lossis kho cov hom phiaj.
2. RNA kho thiab tshawb fawb
Kev sib xyaw ua ke hauv kev tsim kho MRN, Sirna, Antisense Oligonucleides (Asos), thiab aptamers nrog kev txhim kho kev ruaj khov thiab ua haujlwm.
2'-o-Metyl kev hloov kho pab txhawb kom tau RNA tsis kam mus rau Nuclees thiab txo cov immunogenicity.
Pab tau nyob rau hauv kev kawm RNA qauv-ua haujlwm kev sib raug zoo thiab kev sib cuam tshuam protein.
3. EpitransCRIPTOMICTOMICS THIAB MOLECAT Biology
Pab tswj cov synthesis ntawm RNA alolecules mimicking ntuj epitransectomic hloov kho.
Pab tshawb xyuas qhov kev tshawb nrhiav tau hloov kho li cas cuam tshuam rau kev txhais lus, Spricing, thiab RNA-protein kev sib cuam tshuam.
Cov txiaj ntsig
Txhim Kho RNA stability: Qhov 2'-O-Metyl hloov kho tau tshwm sim los ntawm cov kev sib tw hauv tsev no txhim kho kev ruaj ntseg ntawm RNA tawm tsam enzymatic degradation.
Txo kev imbunogenicity: Hloov RNA oligonucleights synthesized nrog no phosphoramidite no qhia kev ua kom tsis muaj zog ntawm kev tiv thaiv kab mob ntawm kev tiv thaiv kab mob.
Cov pab pawg neeg siab ncaj ncees: Cov pab pawg tsim kev tiv thaiv muaj txiaj ntsig txuag tau, High-Comme RNA synthesis nrog ua kom haum ntawm cov nucleotides.
Versatility: Ua rau Tsim Kev Cai Rna RNA cov molecules rau kev kho cov kev txhim kho, kev ua yeeb yam molecular, thiab kev tshawb fawb molecular, thiab kev tshawb fawb molecular, thiab kev tshawb fawb molecular, thiab kev tshawb fawb thiab cov qauv kev kawm.
Tag
5-O-DMT-2-O-Me-I-RA (N-BZ) -3-Cedpa (CASCIATIONS, tseem ceeb rau cov tshuaj-theem ntawm cov tshuaj-ntsuas hluav taws xob RNAlonucleotides. Nws pab cov kws tshawb nrhiav thiab cov kws kho mob tsim tawm los tsim cov qauv ruaj khov nrog cov ntawv thov hauv RNA cov kev tshawb fawb txog kev tshawb fawb biology. Nws tshwj xeeb tiv thaiv pawg thiab tshuaj kho mob kom ua rau muaj kev ncaj ncees heev, txhim kho RNA ruaj khov, thiab txo cov immunogenicity hauv cov khoom siv roj hluavtaws.
Cim npe nrov: 5-O-DMT-2-O-Me-I-RA (N-BZ) -3-CedpaCla-1-O-DMT-2-O-D-me (N-BZ)-丨 CASE 110782-31-5 manufacturers, Chaw Tsim Tshuaj, Hoobkas
