Hangzhou Lep Chem Co., Ltd. yog ib qho ntawm cov neeg tsim khoom lag luam thiab cov khoom lag luam ntawm (5-fluorophenloxazolidin-2-ib tug CAS CAS 444335-16-4 hauv Suav teb. Txais tos rau kev lag luam wholesale kev cai ua cov tshuaj lom neeg cov khoom lag luam ntawm cov nqi sib tw los ntawm peb lub hoobkas. Rau cov khoom lag luam pheej yig tshaj, tiv tauj peb tam sim no.
Cov lus qhia
| Zog: | Tawm dawb rau dawb tawv |
| Purity (HPLC): | 99% min |
| Assay: | 98.0~102.0% |
| Kev txheeb xyuas (HPLC): | Kev muag khoom ntawm cov qauv conforms lub ntsiab siab tseem ceeb rau qhov qauv ntawm tus qauv (± 0.5 min) |
| Lwm yam tshuaj (hplc) -} ib leeg impurity: | 0.5% max |
| Lwm yam tshuaj (HPLC) - ishomer: | 0.5% max |
| Residue ntawm ignition: | 1.0% max |
| Poob rau ziab: | 1.0% max |
Cov Ntawv Thov
(5R) {{- 3- (4-Bluorophenyl)-5-Fluorophenylsloks siv feem ntau hauv cov tshuaj synthesis thiab tshuaj chemical. Nws oxazolidinone tseem ceeb, ua ke nrog cov nkauj halogen, ua rau nws lub tsev muaj txiaj ntsig zoo rau kev txhim kho cov tshuaj tua kab mob, thiab lwm yam kev tiv thaiv kab mob biologically dhia. Qhov sib xyaw ua ke ntawm soreochemethyl ua haujlwm tso cai rau xaiv cov kev hloov tshuaj uas tsis muaj ntau ntau ntxiv nrog cov khoom siv hluav taws xob muaj ntau yam. Nws yog nquag ua hauj lwm hauv cov qauv kev sib raug zoo (SAR) kev kawm kom ua kom zoo rau cov yeeb tshuaj potency, xaiv cov khoom siv, thiab metabolic ruaj khov. Ib qho ntxiv, nws ua haujlwm ua ntej ua ntej rau kev npaj ntawm kev txhim kho ntawm kev txhim kho ntawm kev kho cov kab mob uas muaj peev xwm tiv taus cov kab mob uas tsis tiv thaiv cov kab mob.
Cov txiaj ntsig
Cov txiaj ntsig ntawm (5R) -}}}}}}} (4 {{14} vi {14} Vomsatility Volity, thiab hluavtaws hluavtaws. Lub (5R) -Configuration muab cov kev tswj hwm cov kev ncaj ncees, uas yog qhov tseem ceeb rau kev tswj hwm cov roj ntsha uas xav tau hauv cov khoom sib txuas. Nws cov pab pawg hydroxsyl muaj cov khoom siv reactive rau kev derivatization ntxiv, txhim kho tshuaj lom neeg hauv kev tsim tshuaj. Lub xub ntiag ntawm bromine thiab fluorine atoms ntawm lub nplhaib aromatic txhim kho tshuaj lom neeg, thiab kev xaiv ua rau cov hom phiaj molecules. Ntxiv mus, Oxazolidinone Scaffold yog qhov zoo rau nws lub luag haujlwm hauv cov qauv lwg me me, pab txhawb kev ruaj khov thiab chaw muag tshuaj. Nws cov kev sib raug zoo nrog ntau txoj kev txuas thiab hloov cov nqi kev ua kom muaj txiaj ntsig zoo thiab kev txo qis cov txiaj ntsig zoo thiab kev txhawb nqa hauv cov tshuaj kev tshawb xyuas.
Tag
(5R) -}}} {- (4-fluorophenop-2-Fluorophenop-2-Fluorophenople thiab Heterocyclic Tebchaw. Nws tshwj xeeb ua ke ntawm cov stereochemical precision, reactive kev ua haujlwm, thiab halogenated cov qauv muaj ntxhiab ua kom nws tsis pom kev zoo nkauj, cov kev tshawb fawb tau ua rau cov khoom siv. Los ntawm kev tsim cov txheej txheem zoo ntawm cov txheej txheem ua ke, cov kab ke no tseem ua rau muaj lub luag haujlwm tseem ceeb hauv kev txhim kho ntawm kev tsim kho tom ntej.
Cim npe nrov: (5R) -3- (4-bromo-3-fluorophenylasxazolidin-2-Fluorophenloxazolidin-2-Fluorophenin-2-(5-fluorophenin-2-(5-Fluorophenin-2-(5-Fluorophenin-2-(5-Fluorophenin-2-(5-Fluorophenin-2-(5-Fluorophenin-2-(5-Fluorophenin-2-(5-Fluorophenin-2-(5-Fluorophenin-2-(5-Fluorophenin-2-(5)
