Hangzhou Lep Chem Co., Ltd. yog ib qho ntawm cov neeg lag luam thiab cov khoom siv fluoridinyl) -1,2-benzisoxzole hydrochloride 丨 CAS6463-13-3 hauv Suav teb. Txais tos rau kev lag luam wholesale kev cai ua cov tshuaj lom neeg cov khoom lag luam ntawm cov nqi sib tw los ntawm peb lub hoobkas. Rau cov khoom lag luam pheej yig tshaj, tiv tauj peb tam sim no.
Cov lus qhia
| Zog: | Dawb rau tawm - hmoov dawb |
| Assisy (hplc): | 98% rau 102% |
| Daim qhia npe: | IR / HPLC |
| Lwm yam tshuaj (hplc) -} ib leeg impurity: | 0.2% max |
| Lwm yam tshuaj (hplc) -}} tag nrho impurities: | 0.5% max |
| Poob rau ziab: | 0.5% max |
Cov Ntawv Thov
6 {- Fluoro {}} 3- (4-benzisoxyl)-(4-benzisoxyl)-1- Tshwj xeeb hauv synthesis ntawm Central Nervous System (Cns) Nquag. Nws Benzisoxazole cov tub ntxhais, ua ke nrog cov fluorine-hloov cov khoom siv recomatic, ua rau nws muaj ntau yam tshuaj tiv thaiv cov tshuaj. Nws yog nquag ua haujlwm hauv cov tshuaj chemistry rau synthesis ntawm cov lus sib txuas, dopamine, lossis cov tshuaj tiv thaiv kab mob, thiab lwm yam kev ua kom zoo nkauj. Cov ntsev ntawm hydrochloride ua kom zoo dua qub solubility thiab ruaj khov, suav nrog alkylation, acylation hloov pauv. Ib qho ntxiv, nws ua hauj lwm ua tus lej tseem ceeb hauv kev ua haujlwm sib raug zoo (SAR) kev ua kom zoo rau cov tshuaj ntawm cov tshuaj kev loj hlob.
Cov txiaj ntsig
Cov txiaj ntsig ntawm 6 {{{{}} fluoro {}}}}}}}}}} (4-benzisoxlatility, thiab cov khoom siv hluav taws xob, thiab cov kws muag khoom siv hluav taws xob. Fluorine atom Exchances metabolic ruaj thiab lipophilicity ntawm cov dej ntws hauv qab, uas tuaj yeem txhim kho Bioavailability thiab receptor xaiv. Nws cov pab pawg piperidineyl muab cov vev xaib reactive rau derivatization thiab pab txhawb rau cov khoom siv hluav taws xob hauv CNS-active molecules. Lub nplhaib benzisoxazole txeeb chaw thiab teeb meem, txhim kho cov kev sib cuam tshuam nrog roj ntsha. Lub fydrochloride daim ntawv ua kom tuav tau zoo dua, solubility, thiab reproducibility thaum synthesis, ua rau nws cov kev tshawb fawb thiab kev lag luam kev lag luam. Cov yam ntxwv no tau tso cai rau cov neeg siv tshuaj tua cov kws tsim qauv thiab synthesize bioactive molecules nrog txhim kho kev ua tau zoo thiab kev nyab xeeb profiles.
Tag
6 {- Fluoro {}}}}}} 3- (4-benzisoxyl)-(1-benzisag nrho cov tshuaj muaj txiaj ntsig zoo hauv kev txhim kho cov tshuaj ntawm neuroactive Nws sib txuas ntawm cov qauv nruj, fluorine hloov chaw, thiab cov tshuaj lom neeg ua haujlwm ua rau nws tsis tseem ceeb hauv kev tshawb xyuas tshuaj chemistry. Los ntawm kev ua kom meej meej molecular kev hloov kho thiab cov hluavtaws muaj txiaj ntsig zoo ntawm cov kws tshuaj sib xyaw, qhov kev txhawb nqa tshiab txuas ntxiv txhawb kev txhim kho thiab kev nce qib hauv kev txhim kho kev lag luam.
Cim npe nrov: 6-fluoro-3- (4-benzisoxyl) -1,2-benzisoxanole hydrochloride 丨 Cas 84163-13-3 Cov Chaw Tsim Tshuaj, Chaw Tsim Tshuaj, Hoobkas
