Cov lus qhia
| Qib: | BP2018 / USP42 |
| Zog: | Dawb lossis yuav luag dawb crystalline hmoov |
| Assay: | 99.0-101.0% (suav rau ntawm qhuav) |
| Solubility: | Sparingly soluble hauv dej, ywj siab soluble hauv cawv, soluble me ntsis hauv methylene chloride |
| Daim qhia npe: | |
| Melting taw tes: | 168-172.0 Degree |
| IR: | Sib xws nrog cov spectrum tau nrog paracetamol crs |
| Related tshuaj: | |
| Ipurity J (chloroacetanilide): | 10 ppm max |
| Irfurity k (4-aminophenol): | 50 ppm max |
| Impurity f (4-nitrophenol): | 0.05% max |
| Lwm yam impurity: | 0.05% max |
| Tag nrho lwm cov impurities: | 0.1% Max |
| Poob rau ziab: | 0.5% max |
| Residue ntawm ignition: | 0.1% Max |
| Residual cov kuab tshuaj: | |
| Acetic acid: | 0.5% max |
| Microbial txwv: | |
| Tag nrho cov kab mob aerobic: | 2000 CFU / G Max |
| Sib xyaw pwm thiab cov poov xab: | 200 cfu / g max |
| Escherichia coli: | Kev tsis nyob |
Cov Ntaub Ntawv Thauj
|
Chaw ua uas tsis tau haus |
Kev qhia tshwj xeeb |
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UN NUM |
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Hom |
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Cov Pab Pawg |
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Hs code |
2924292000999 |
|
Ruaj khov & rov ua |
Lub teeb rhiab. Ruaj khov. |
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Chaw ntim khoom |
Cia cia rau hauv ib qho chaw qhuav, txias thiab muaj cua zoo. Khaws kaw kom nruj. |
|
Mob kom tsis txhob |
Raug rau lub teeb |
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Lub thawv |
Cov Ntawv Thov
1. Kev lag luam kev lag luam
Dav siv los ua analgesic thiab antipyretic
Txo qhov mob (mob me me) thiab kub taub hau.
Ib qho ntawm cov feem ntau siv cov khoom siv sib txawv (OTC) cov tshuaj ntsuab.
Siv los ua cov tshuaj muag muag lossis ua ke nrog cov qauv nrog:
Tshuaj kas fes
Chaws code
Diphenhydramine
Phenyphrine
Muaj nyob rau hauv ntau cov ntawv ntau:
Cov ntsiav tshuaj, tsiav tshuaj, raug tshem tawm, phoovs, kom cov kev daws teeb meem, thiab cov kev daws teeb meem.
2. Nruab nrab hauv cov tshuaj synthesis
Ua hauj lwm ua qhov pib cov khoom siv rau cov xwm txheej ntawm:
Lwm yam kev ua haujlwm thiab antipyretics
Ib txhia zas xim intermediates thiab tshuaj tua kab
3. Biochemical Kev Tshawb Fawb
Siv raws li kev siv txuas rau kev kawm:
Hepatotoxicity mechanisms (vim nws daim siab metabolism)
Oxidative Kev Nyuaj Siab thiab Cov Patholic Pathways hauv daim siab
Cov txiaj ntsig
✔ Ua Tau Zoo
Ua kom pom kev sib zog kom zoo thiab kho kom zoo rau cov xwm txheej xws li:
Mob taub hau
Hniav
Mob ntsws
Kev coj khaub ncaws kev coj khaub ncaws
Mob khaub thuas thiab khaub thuas
✔ Qhov qis qis plab hnyuv voos
Tsis zoo li NSAIDs (piv txwv li, ibuprofen, aspirin), paracetamol:
Muaj tsawg heev rau kev ua kom lub plab zom mov
Tsis arhibit cox-1 yig, txo cov kab mob ulcer
✔ Muaj kev nyab xeeb thaum txhaj tshuaj tiv thaiv
Muaj kev nyab xeeb rau cov menyuam yaus thiab cov neeg laus thaum siv raws li qhia
Feem ntau pom zoo rau cov neeg mob uas mob rau mob txhab lossis cov uas tsis tuaj yeem tiv thaiv NSAIDs
✔️ Versulation Xaiv
Tuaj yeem tsim ua kua, khoom, lossis cov ntawv txhaj
Tso cai rau kev ua haujlwm nrawm nrawm hauv cov khoom xa tawm (piv txwv li, Iv Paracetamol)
Tag
4-acetamenol (paracetamol / acetaminophen) yog lub pob zeb hauv pob zeb hauv cov khoom siv niaj hnub rau nws cov tshuaj tiv thaiv thiab tshuaj tiv thaiv. Nws yog kev ntseeg siab rau kev mob mob thiab kub taub hau nrog cov ntaub ntawv kev nyab xeeb nyab xeeb thaum siv lub luag haujlwm. Ntxiv nrog rau nws cov kev siv tshuaj kho, nws plays lub luag haujlwm hauv tshuaj lom neeg, kev tshawb fawb, ua rau muaj ib qho tseem ceeb tshaj plaws hauv cov tshuaj thiab chaw kuaj mob.
Cim npe nrov: 4-ACTAMIDOPHENOL 丨 CAS 103-90-2, Tuam Tshoj 4-acetamenolenol 丨 CAS 103-90-2 tuam ntxhab, Hoobkas
