Cov lus qhia
| Zog: | Dawb rau off-dawb hmoov |
| Purity (HPLC): | 99.0% min |
| Daim qhia npe: | HPLC & IR |
| Melting taw tes: | 150 Qib rau 155 Qib |
| Dej: | 0.5% max |
| Residue ntawm ignition: | 0.1% Max |
| Cov Hlau Hnyav: | 20 PPM Max |
| Related tshuaj: | |
| - IFPURURURING A: | 0.10% Max |
| - Illpurity C: | 0.10% Max |
| - Tag nrho cov impurities: | 1.0% max |
| - tej impurcified impurity: | 0.10% Max |
| Residual cov kuab tshuaj (GC): | |
| - Dichhloromethane: | 600 ppm max |
| - Ethyl acetate: | 5000 ppm max |
| - Ethanol: | 5000 ppm max |
| - TOLUES: | 890 ppm max |
| - Methanol: | 3000 PPM Max |
| - Coproproyl Cawv: | 5000 ppm max |
| - TetrahyDrofuran: | 720 ppm max |
| - N-Heptane: | 5000 ppm max |
| - Acetoniturile: | 410 ppm max |
Cov Ntaub Ntawv Thauj
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Chaw ua uas tsis tau haus |
Kev qhia tshwj xeeb |
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UN NUM |
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Hom |
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Cov Pab Pawg |
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Hs code |
2932190090303 |
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Ruaj khov & rov ua |
Cov khoom lag luam ruaj khov nyob rau hauv cov qauv ambient ambient. |
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Chaw ntim khoom |
Khaws kaw kom nruj. Khaws raws li cov ntaub ntawv teev rau ntawm cov khoom ntxig. |
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Mob kom tsis txhob |
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Lub thawv |
Cov ntaub ntawv raug
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Chaw ua uas tsis tau haus |
Kev qhia tshwj xeeb |
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Lub peev xwm |
1mt / hli |
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Hov ntau |
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Lub teb chaws tseem ceeb |
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Peev Xwm / Batch |
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Paub lawm |
Ntau lawm txij xyoo 2010 |
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Ntxiv rau |
Cov Ntawv Thov
1. Kev kho mob hom 2 Ntshav Qab Zib Mellitus
Kev Kho Mob lossis Kev Kho Mob Ua Si nrog rau lwm cov tshuaj antidiabetic (piv txwv li, manformin, insulin).
Txhim kho glycemic tswj los ntawm kev nce kev tso zis ntau dhau kev ywj pheej ntawm insulin kev tso zais.
2. Mob plawv kev phom sij
Empagliflozin yog FDA- thiab EMA pom zoo rau kev txo qis kev pheej hmoo ntawm cov kev pheej hmoo ntawm cov neeg mob plawv ntawm cov neeg laus nrog T2DM thiab tsim cov kab mob plawv.
Qhia kom txo qis hauv tsev kho mob rau lub plawv tsis ua tiav (HF) hauv ob tus neeg mob ntshav qab zib thiab cov neeg mob ntshav qab zib.
3. Lub plawv dhia tsis ua haujlwm (HFF thiab HFPEF)
Siv rau hauv kev kho lub plawv tsis ua haujlwm nrog kev txo qis ejection (HFREF) thiab khaws cia feem (hfpef).
Txo tus nqi pw hauv tsev pw thiab txhim kho kom zoo ntawm lub neej thiab ua haujlwm tshwm sim hauv cov neeg mob HF.
4. Ntev tus kabmob raum (CKD)
Empagliflolomozin tau qhia txog cov txiaj ntsig ntawm Lub raum, suav nrog qeeb zuj zus ntawm CKD thiab txo cov proteinuria.
Pab tswj cov lus qhia txog Glomerular (GFR) raws sijhawm.
Cov txiaj ntsig
✅ Ua kom zoo Glycemic tswj
Txo hba1c los ntawm ~ 0.6-0.9% raws li monotherapy lossis hauv kev sib xyaw.
Tsawg txoj kev pheej hmoo ntawm hypoglycemia thaum siv tsis muaj insulin lossis sulfonyhluras.
✅ Kev Tiv Thaiv Kab Mob
Qhia kev txo qis hauv plawv plawv tuag hauv Empa-tso tawm cov txiaj ntsig kev sim.
✅ Qhov hnyav txo
Ua rau muaj kev coj lub cev yuag me me (~ 2-3 kg), muaj txiaj ntsig rau cov neeg rog dhau los yog cov neeg mob hnyav nrog t2dm.
Muaj Kev Txiav Txim Siab Ntshav
Txo cov ntshav ntshav siab (~ 4-5 mmHg) vim diuretic-zoo li nyhuv.
Renal tiv thaiv cov teebmeem
Slows kev ua tiav ntawm cov ntshav qab zib nephleels thiab txo albuminuria.
✅ Ib zaug ib hnub kev tswj hwm qhov ncauj
Txhim kho cov neeg mob tus neeg mob adherence vim kev siv zog tag nrho.
Tag
Empagliflozin (CAS 864070-44-0) yog ib qho zoo tshaj plaws SGGT2 inhibor siv tsis tsuas yog kho hom ntshav qab zib hom xwb tab sis kuj rau kev pheej hmoo txoj kev pheej hmoo. Nrog muaj txiaj ntsig kev tuag, Glycemic tswj, thiab kev tiv thaiv ntawm lub plawv thiab raum, nws tau dhau los ua kev kho mob hauv pob zeb hauv kev lag luam metabolic thiab cov hlab ntsha.
Cim npe nrov: Empagliflozin are Cas Cas 864070-44-0, Tuam Tshoj Empagliflozin are Cas 864070-44-0 Manufacturers, Chaw Tsim Tshuaj, Hoobkas
