Streptozocin 丨 CAS 18883-66-4

Streptozocin 丨 {18883-66-4 yog ib qho tshwm sim ib txwm muaj uas feem ntau siv cov qog nqaij hlav. Nws yog antineopastic (tiv thaiv mob cancer) cov tshuaj uas yog tshwj xeeb tshaj yog tiv thaiv pancreatic neuroendocrine hlav. Streptozocin yog muab tau los ntawm cov kab mob Streptomyces Achromogenes thiab kuj tseem siv hauv kev sim ua kom muaj kev xaiv kho cov kab mob insulin-kev ua kom lub hlwb.
Mechanism ntawm Kev Ua
Streptoozocin lub tshuab ntawm kev nqis tes ua cuam tshuam nrog nws lub peev xwm los alkylate DNA, tshwj xeeb tshaj yog hauv pancreatic beta hlwb. Los ntawm kev qhia ib pawg alkyl rau hauv DNA, nws cuam tshuam rau DNA cov txheej txheem replication txheej txheem, ua rau kev tuag cell tuag. Streptozocin 丨 {18883-66-4} muaj qhov ua tau los kho cov qog nqaij hlav panceric ntawm cov qog nqaij hlav (tshwj xeeb, insulinomas).
Vim tias cov hom phiaj streptozocin sai sai faib cov hlwb thiab muaj tshuaj lom ntau heev rau qee hom cytotoxic tshuaj cytotherapy tus neeg sawv cev. Nws yog xaiv ntau toxic rau neuroendocr cov qog nqaij hlav, tshwj xeeb tshaj yog cov neeg nyob hauv lub cev, uas yog lub luag haujlwm rau insulin zais cia.

1.Cancer Kev Kho:
Pancreatic NeurendCrine Tumrs: Streptzcin 丨 18883-66-4 yog feem ntau siv nyob rau hauv kev kho f pancrine tumrs (tumrs uas prduce ntau dhau ntawm insulish). Nws yog qhov ua tau zoo rau kev txo qis tumr loj thiab imprick hauv cov neeg mob uas muaj mob qog nqaij hlav cancer adjectatic insulinmas.
Nws yog siv los ua ib feem ntawm kev ua raws li kev ua yeeb yam ntawm kev ua yeeb yam ntawm CMbinatin hauv Cmbinatin nrog} fluururacil (} fu) r
2.
Beta-cell kev rhuav tshem: streptzcin 丨 18883-66-4}}}}}} puas muaj nyob hauv cov tsiaj uas muaj kev sim siab rau cov tsiaj txhu (xws li rdents). Qhov MDEL no muaj txiaj ntsig hauv kev tshawb fawb ntshav qab zib thiab nkag siab txog cov lus edphysilgy f insulin-prducing hlwb. Tus xaiv tshuaj Txicity f streptzcin twards pancreatic beta hlwb ua rau nws muaj nuj nqis hauv cov hom kev tshawb fawb.
Nws tau siv t induce hom 1 mob ntshav qab zib hauv cov tsiaj sim ua rau cov kab mob f tus kab mob thiab T Steistic Kho cov kev kho mob.
3.chemtherapy fr thercers:
Thaum nws cov ntawv sau ua ntej yog nyob rau hauv kev kho mob cancer f pancreatic

Streptoozocin 丨 {18883-66-4 Yog cov tshuaj lom neeg tshwj xeeb yog cov tshuaj tiv thaiv mob pancors, tshwj xeeb yog cov tshuaj insulinomas, los ntawm kev xaiv cov tshuaj insulin-tsim cov ntshav hauv cov hlab ntsha. Nws kuj tseem muaj txiaj ntsig zoo nyob rau hauv kev sim ntshav qab zib sim vim nws lub peev xwm los rhuav tshem cov borcreatic borca ​​hlwb. Txawm hais tias nws kho cov txiaj ntsig, streptozocin muaj ntau yam tshwm sim tshwm sim, suav nrog lub raum lom, cov teeb meem pob txha caj ces. Nws siv yuav tsum ua tib zoo saib xyuas cov muaj nuj nqi raum, ntshav suav, thiab qib elecolyte. Streptozocin yuav tsum tsuas yog siv rau hauv cov chaw kuaj mob tsim nyog nrog kev saib xyuas ze.