Cov lus qhia
| Teem nqi | USP |
| Kev tshwm sim | Dawb lossis tawm -} e} crystalline hmoov |
| Assay (t ntawm qhuav degred) | 98% ~ 101% |
| Purity (hplc) | 99% min |
| Ywg dej | 0.5% max |
| Daim qhia npe | IR B Duav 50 mg hauv 5 ml ntawm acetone thiab dilute nrog dej rau 10 ml. Ntxiv 1 des ntawm 2 n sulfuric acid, ces ntxiv 4 tee ntawm Tsiab Nyiaj Nitrate Ts: Tsis muaj Openalescence tau pom tam sim (tsis tuaj ntawm chloride ion). Sov cov tshuaj ntawm ib lub chav da dej, opalescence muaj (muaj cov tshuaj chlorine oneizable). |
| So | Xim: tsis muaj xim lossis tsaus muag Turbidity: ntshiab Txoj Kev: 100 mg / ml / ml hauv ethanol |
| Melting taw tes | 65-69 degree |
| Residual Hnyav | Ethyl Acetate: 5000 PPM Max Isopropanol: 5000 PPM Max Toluene: 890 ppm max N - hexane: 290 ppm max |
Cov Ntawv Thov
Chlorambucil (CAS 305-03-3) is a well-established chemotherapeutic drug belonging to the nitrogen mustard class of alkylating agents. Nws lub ntsiab lus tseem ceeb yog nyob rau hauv kev kho mob ntawm qee lub cancer, tshwj xeeb yog hematologic malignon, tsis-hodgphoma, thiab waldenström macroglobulinemia. Nws ua haujlwm los ntawm kev sib txuas lus sib txuas nrog DNA, kev sib tw-txuas uas tsis pub ua kev rov ua dua tshiab thiab kev sau ntawv, thaum kawg ua rau ntawm tes tuag. Chlorambil feem ntau muab cov lus qhia hauv cov ntsiav tshuaj, uas muab cov tshuaj ntsiav yooj yim piv rau ntau lwm cov kws kho mob tshuaj uas xav tau kev tswj hwm kev tswj hwm. Vim nws cov hauj lwm zoo thiab suav tau tias yog cov chaw tshuaj xyuas cov kws kho mob, tshwj xeeb tshaj yog rau cov neeg mob uas tsis tuaj yeem tiv thaiv kev txhoj num ntau yam siv tshuaj kho mob.
Cov txiaj ntsig
Cov txiaj ntsig ntawm chlorambucil yog khi rau nws cov kev kho kom zoo thiab chaw kho mob tswj. Nws muaj keeb kwm ntev ntawm kev tswj hwm ntawm kev tswj ntshav -} cov qog nqaij hlav, feem ntau ua rau kev tiv thaiv kab mob tseem ceeb lossis kev txhim kho kom txhim kho. Ua ib qho tshuaj kho mob, nws muab ntau dua rau cov neeg mob thiab txo qhov xav tau ntawm kev mus ntsib hauv tsev kho mob ntau zaus. Chlorambil feem ntau yog feem ntau ua siab ntev rau kev ua tib zoo tswj hwm cov koob tshuaj, ua rau muaj kev xaiv rau cov neeg mob laus lossis cov neeg ua haujlwm ntawm cov neeg ua haujlwm tsis tuaj yeem tiv thaiv cov tshuaj kho mob. Nws tseem ua haujlwm rau kev kho tus briding, pab kom muaj kev tiv thaiv kab mob ruaj khov thaum npaj cov neeg mob rau cov hlwb pob txha lossis pob txha tsheb. Nws cov kev txiav txim siab tau thiab kev ua yeeb yam uas cia cov kws kho mob txhawm rau kho cov kev kho mob kom zoo, ntsuas kev ua tau zoo nrog rau sab- Cov kev tswj hwm sab.
Tag
Hauv kev xaus, Chlorambucil tseem yog cov tshuaj tseem ceeb ntawm kev kho tshuaj hauv kev kho ntshav ntawm hematologic cancers. Nws qhov ncauj muaj, tsim cov ntaub ntawv hauv qab, thiab tswj tau sab nraud}}} Qhov kev xaiv rau cov neeg mob yuav tsum muaj txiaj ntsig zoo dua qub. Los ntawm kev tswj hwm rau kev tswj tus kab mob, txhim kho neeg ua haujlwm zoo ntawm lub neej, thiab ua haujlwm ua kev kho mob ntxiv los ntawm kev ua kom zoo nkauj niaj hnub thaum thov kev saib xyuas kev kho mob niaj hnub no.
Cim npe nrov: chlorambucil 丨 305-03-3, Suav teb chlorambucil are 305-03-3 cov tuam ntxhab, cov chaw tsim khoom, chaw tsim khoom
