Cov lus qhia
| Kev tshwm sim | Ib tug dawb crystalline hmoov |
| Lam xav | 99.0%~101.0% |
| Daim qhia npe | IR / HPLC |
| So | 1g coj mus ua piv txwv nyob rau hauv 10 ~ 30 ml dej |
| Cov tsos ntawm kev daws teeb meem | Ntshiab thiab tsis muaj xim |
| Dej Cov Ntsiab Lus | Tsis ntau tshaj 0.5% (siv 0.4g) |
| Cov hlau hnyav | Tsis ntau tshaj 0.001% |
| Residue ntawm ignition | Tsis pub ntau tshaj 0.1% |
| Kev coj dawb huv | Tsis pub tsawg tshaj 99.5% |
| Tus neeg Iypurity | Tsis pub ntau tshaj 0.1% |
| Tag nrho cov impurities | Tsis ntau tshaj 0.5% |
| Chiral purity (ee) | Tsis pub tsawg tshaj 99.0% |
| Muaj feem cuam tshuam a | Tsis ntau tshaj 0.5% |
| Residual cov kuab tshuaj | Methanol: Tsis ntau tshaj 3000 PPM Ethyl acetate: tsis ntau tshaj 5000 PPM TetraYDROFURAN: Tsis ntau tshaj 720 ppm |
| Kev ceev kev cai | Cov khoom ua raws li cov ntaub ntawv tshwj xeeb USP 32 |
Cov Ntawv Thov
Dorzolamide hydrochloride (CAS 130693 - 82}} 2}}}} pacoucoma cov tshuaj. Nws lub ntsiab lus tseem ceeb yog kom txo qis siab xav tau intraitocular siab (iop) nyob rau hauv cov neeg mob nrog qhib-lub glaucoma lossis ecular bypertension. Dorzoloside muaj nuj nqi raws li carbonic anhydrase ntau lawm, tsawg dua cov kua zaub ua si hauv lub qhov muag, uas nyob hauv qab qis iop. Nws yog ib txwm tsim qauv raws li kev kho mob ophthalmic, txawm yog kev kho mob los yog ua ke nrog lwm cov neeg sawv cev xws li beta-blockers, kom muab kev tswj hwm txhim kho ntawm lub siab xav tau. Nws cov ntsiab lus ntawm kev coj tswj hwm tso cai rau kev ua yeeb yam nrog kev sib raug zoo.
Cov txiaj ntsig
Cov txiaj ntsig ntawm dorzolide hydrochloride yog cuam tshuam ncaj qha nrog nws cov kev ua tau zoo, kev nyab xeeb, thiab kev tsim nyog hauv kev tswj hwm cov kev tswj hwm txhawb nqa intraitocular. Los ntawm xaiv tau carbonic anhydrase nyob rau hauv ciliary cov txheej txheem ntawm lub qhov muag, nws muab kev pab tiv thaiv cov neeg mob optic thiab khaws cia lub zeem muag hauv cov neeg mob nyuaj. Cov Txwj Laus Cov Txheej Txheem Me Me Cov teeb meem kev mob phiv piv rau qhov ncauj carbonic anhydrase inhibitors, ua rau nws haum rau ntev- sim kho. Nws tseem ua rau lwm cov tshuaj ocular, muab cov teebmeem ua haujlwm synergistic hauv kev sib xyaw ua ke rau kev tswj hwm tus kab zoo dua. Nws cov ruaj khov thiab sib xyaw nrog ophthalmic formulations kom tau txais kev kho kom zoo ib yam thiab neeg ua siab ntev.
Tag
Hauv kev xaus, dorzolamide hydrochloride yog ib qho tseem ceeb anti - Glaucomal siab siv los txo lub zeem muag siab rau cov neeg mob uas muaj kev kub ntxhov. Nws lub hom phiaj ua haujlwm, kev ua tau zoo, thiab kev tsim txom tau ua rau nws xaiv tau muaj txiaj ntsig hauv OPHThalmic kev saib xyuas. Los ntawm kev tsim cov kab mob kis tau zoo thiab txhawb nqa ntev-} hydrochloride ua lub luag hauj lwm tseem ceeb hauv niaj hnub no kev kho mob.
Cim npe nrov: Dorzolomide Hydrochloride 丨 cas CAS 130693-82-2, Tuam Tshoj dorzolomide Hydrochloride 丨 CASİ0693-82-2 tuam ntxhab, Hoobkas
