Cov lus qhia
| Kev tshwm sim | Dawb rau off-dawb khoom |
| Kev coj dawb huv | 99% min |
| So | Soluble hauv dichhloromethane thiab insoluble hauv cyclohexane |
| Keto epoxide | 0.1% Max |
| Lub saw loj loj | 0.5% max |
| Ib Leeg Cav | 0.5% max |
| Dej Cov Ntsiab Lus | 0.5% max |
Cov Ntawv Thov
1. Anticancer Tshuaj - protasove inhibitor
Carfilzomib yog ib qho kev siv proiskas thib ob uas muaj cov tshuaj tiv thaiv rau ntau yam myeloma, tshwj xeeb hauv kev hloov pauv lossis cov teeb meem refactory.
Nws xaiv thiab irreversibly inhibits lub chmmotrypsin-zoo li kev ua ntawm 20s protasation, ib qho tseem ceeb ntawm txoj kev ua kom muaj protein.
2. Kev kho mob ntawm ntau Myeloma
Pom zoo rau cov neeg mob uas tau txais kev kho mob ua ntej, suav nrog Bortezomib thiab immunomodulatory siv yeeb tshuaj.
Feem ntau siv ua ke nrog lwm cov tshuaj xws li lenidomomide thiab dexamethasone rau kev kho cov nyhuv txhim kho.
3. Kev Tshawb Fawb
Kev tshawb fawb hauv Biomedical kev tshawb fawb los kawm cov protein degradation, cellular poptosis, thiab procolease muaj nuj nqi.
Pab nkag siab lub luag haujlwm ntawm kev tiv thaiv kev tiv thaiv kab mob cancer thiab lwm yam kab mob.
Cov txiaj ntsig
✅ muaj zog thiab xaiv cov neeg hauv cov neeg nyob hauv no
Irreversible khi ua kom muaj kev txwv tsis pub muaj kev txwv tsis pub muaj prohiecition.
Txo cov tshuaj lom neeg lom tau piv rau thawj-tiam neeg inhibitors
Txhim kho kev nyab xeeb profile muab piv rau Bortezomib, nrog tsawg dua-phiaj cuam tshuam.
✅ Ua tau zoo nyob rau hauv resistant ntau myeloma
Qhia cov haujlwm hauv cov neeg mob kom tswj tau lwm txoj kev kho.
✅ Lub Chaw Tswj Xyuas Kev Nyab Xeeb
Tso cai tswj kev txhaj tshuaj thiab bioavailability hauv cov chaw kuaj mob.
Tag
Carfilzomib (CASE 868540-170-17-4) yog lub zog heev thiab xaiv cov prodentive profenteome inhibomitorizing kev kho rau ntau yam Myeloma. Nws cov hom kev ua ntawm kev nqis tes ua thiab txhim kho kev nyab xeeb profile ua rau nws ua tau zoo rau cov neeg mob tiv taus kev kho mob ntxov. Tshaj li nws txoj kev vam meej, Carfilzomib yog qhov txiaj ntsig kev tshawb fawb muaj txiaj ntsig zoo rau kev ua yeeb yam muaj kev tiv thaiv kev tiv thaiv kev tiv thaiv kev tiv thaiv kev tiv thaiv kev tiv thaiv kev tiv thaiv biology thiab undertcoring nws qhov tseem ceeb hauv kev kho cov ntsiab lus thiab scientionic.
Cim npe nrov: Carfilzomib 丨 CASE 868540-170-17-4, Tuam Tshoj Tuam Tshoj Carfilzomib 丨 CAS 868540-17-4 tuam ntxhab, cov chaw muag khoom, Hoobkas
