Hangzhou Leap Chem Co., Ltd. yog ib qho ntawm cov tuam txhab tshaj lij thiab cov chaw muag khoom ntawm 2-deoxy-2-fluoroguanosine 丨cas 78842-13-4 hauv Suav teb. Txais tos rau kev lag luam wholesale kev cai ua cov khoom lag luam ntawm tus nqi sib tw los ntawm peb lub hoobkas. Rau cov khoom pheej yig dua, tiv tauj peb tam sim no.
Specifications
| Qhov tshwm sim | Cov khoom yuav tsum yog dawb los yog yuav luag dawb hmoov |
| Solubility | Clear colorless tov ntawm 50 mg / ml hauv dej |
| Tus Kheej (los ntawm 1H NMR) | Ua raws li cov qauv |
| Purity (HPLC) | 98% min |
| Residue ntawm Ignition | 0.5% max |
| Cov dej noo | 8% max |
Daim ntawv thov
2-Deoxy-2-fluoroguanosine feem ntau yog siv rau hauv kev tshawb fawb tshuaj thiab tshuaj chemistry raws li nucleoside analog. Nws ua haujlwm ua lub tsev thaiv rau kev sib txuas ntawm cov tshuaj tiv thaiv kab mob, tshuaj tiv thaiv kab mob, thiab lwm yam tshuaj kho mob uas tsom mus rau nucleic acid metabolism. Kev hloov fluorine ntawm 2-txoj haujlwm ntawm lub nplhaib deoxyribose txhim kho cov metabolism hauv kev ruaj ntseg thiab tuaj yeem hloov kho qhov sib xyaw ua ke nrog cov enzymes xws li DNA polymerases thiab kinases. Nws yog siv rau hauv kev tsim ntawm prodrugs, hloov kho oligonucleotides, thiab nucleotide derivatives rau kev kawm DNA / RNA synthesis, enzyme inhibition, thiab kev tsim tshuaj. Hauv kev tshawb fawb, nws kuj tseem siv rau hauv kev tshuaj ntsuam biochemical los tshawb xyuas nucleoside thauj, koom ua ke rau hauv DNA, thiab enzyme substrate tshwj xeeb.
Cov txiaj ntsig
Cov txiaj ntsig ntawm 2-Deoxy-2-fluoroguanosine tshwm sim los ntawm nws cov tshuaj lom neeg ruaj khov, bioactivity, thiab cov qauv zoo sib xws rau ntuj nucleosides. Lub fluorine atom txhim kho kev tiv thaiv rau enzymatic degradation thaum tswj lub peev xwm los koom hauv kev sib koom ua ke, uas yog qhov tseem ceeb rau kev siv hauv nucleic acid analog kev tshawb fawb. Nws qhov kev kwv yees ua tau zoo thiab kev sib raug zoo nrog tus qauv nucleoside chemistry pab kom muaj txiaj ntsig zoo ntawm cov khoom siv thiab kev koom ua ke rau hauv oligonucleotides. Qhov sib xyaw ua ke ruaj khov thiab txhais tau hais tias stereochemistry txhawb kev tsim cov txiaj ntsig hauv kev tshawb fawb thiab kev tsim tshuaj, ua rau nws yog ib qho tseem ceeb rau kev kawm cov txheej txheem nucleic acid thiab tsim kev kho mob.
Xaus
2-Deoxy-2-fluoroguanosine yog ntau yam nucleoside analog siv hauv kev tshawb fawb tshuaj thiab nucleic acid chemistry. Nws cov qauv fluorinated muab txhim khu kev ruaj ntseg thiab bioactivity, ua rau txoj kev loj hlob ntawm antiviral, anticancer, thiab oligonucleotide-raws li kev kho mob. Cov khoom no ua rau nws yog ib qho tseem ceeb rau kev tshawb fawb biochemical siab heev thiab kev siv tshuaj chemistry.
Cim npe nrov: 2-deoxy-2-fluoroguanosine 丨cas 78842-13-4, Tuam Tshoj 2-deoxy-2-fluoroguanosine丨cas 78842-13-4 manufacturers, lwm tus neeg, Hoobkas
