Hangzhou Leap Chem Co., Ltd. yog ib qho ntawm cov tuam txhab tshaj lij thiab cov neeg muag khoom ntawm methyl 2-(3s)-3-3-(1e)-2-(7-chloro-2-quinolinyl)ethenylphenyl-3-hydroxypropylbenzoate丨cas 181139-72-0 hauv Suav teb. Txais tos rau kev lag luam wholesale kev cai ua cov khoom lag luam ntawm tus nqi sib tw los ntawm peb lub hoobkas. Rau cov khoom pheej yig dua, tiv tauj peb tam sim no.
Specifications
| Qhov tshwm sim | Yellow khoom |
| Purity | 98.0% min |
| Kev txheeb xyuas | NMR, HPLC |
Daim ntawv thov
Methyl 2-(3S)-3-3-(1E)-2-(7-chloro-2-quinolinyl)ethenylphenyl-3-hydroxypropylbenzoate yog ib qho tshuaj complex intermediate feem ntau siv hauv kev tshawb nrhiav tshuaj thiab tshuaj chemistry. Nws ua haujlwm ua lub tsev tseem ceeb hauv kev sib txuas ntawm bioactive quinoline derivatives thiab cov tshuaj kho me me, tshwj xeeb tshaj yog nyob rau hauv cov kev pab cuam tsom rau cov hlab plawv, paj hlwb, lossis inflammatory pathways. Qhov sib xyaw ua ke yog siv rau hauv cov kev tshawb fawb txog kev sib raug zoo-kev sib raug zoo (SAR) txhawm rau txhim kho lub zog, kev xaiv, thiab cov khoom siv tshuaj pharmacokinetic ntawm cov neeg sib tw tshuaj. Nws cov hydroxypropyl thiab ester functionalities tso cai ntxiv derivatization, ua rau cov kws kho mob ua kom muaj ntau yam analogues rau kev ntsuam xyuas preclinical. Tsis tas li ntawd, nws yog siv rau hauv cov kev tshawb fawb mechanistic, enzyme inhibition assays, thiab receptor-ligand kev sib cuam tshuam kev tshawb fawb los tshawb txog cov tshuaj pharmacodynamics thiab kev ua haujlwm lom neeg hauv kev txhim kho tshuaj thaum ntxov.
Cov txiaj ntsig
Cov txiaj ntsig ntawm qhov sib xyaw no tshwm sim los ntawm nws cov qauv siv ntau yam, stereochemical precision, thiab ntau yam hluavtaws. Lub 3S teeb tsa ua kom ntseeg tau tias cov stereochemistry tau txhim kho kev ua haujlwm lom neeg thiab kev xaiv hauv cov neeg siv tshuaj. Nws pab pawg hydroxypropyl thiab ester tso cai rau kev hloov pauv tshuaj lom neeg, txhawb nqa ntau -theem synthesis ntawm complex molecules nrog siab yield thiab reproducibility. Cov quinoline thiab phenyl moieties pab txhawb rau receptor binding thiab pharmacophore tsim, ua rau cov molecule ib tug tseem ceeb cuab tam rau cov kws kho mob. Cov khoom sib xyaw ua kom muaj kev ruaj ntseg zoo nyob rau hauv cov txheej txheem kuaj mob thiab kev sib raug zoo nrog cov organic solvents, ua kom yooj yim tuav, khaws cia, thiab koom ua ke rau hauv cov txheej txheem hluavtaws siab heev.
Xaus
Methyl 2-(3S)-3-3-(1E)-2-(7-chloro-2-quinolinyl)ethenylphenyl-3-hydroxypropylbenzoate yog ntau yam thiab muaj txiaj ntsig nruab nrab hauv kev tshawb fawb tshuaj thiab kev tshawb nrhiav tshuaj. Nws cov ntsiab lus stereochemical, ntau pawg neeg ua haujlwm, thiab quinoline-based qauv ua kom muaj txiaj ntsig zoo ntawm bioactive molecules thiab pab txhawb kev tshawb fawb SAR. Los ntawm kev txhawb kev xaiv derivatization, optimization ntawm pharmacological zog, thiab preclinical ntsuam xyuas, cov compound no plays lub luag hauj lwm tseem ceeb nyob rau hauv txoj kev loj hlob ntawm tshiab kho mob thiab niaj hnub tshuaj chemistry daim ntaub ntawv.
Cim npe nrov: methyl 2-(3s)-3-3-(1e)-2-(7-chloro-2-quinolinyl)ethenylphenyl-3-hydroxypropylbenzoate 丨cas 181139-72-0, Tuam Tshoj methyl 2-(3s)-3-3-(1e)-2-(7-chloro-2-quinolinyl)ethenylphenyl-3-hydroxypropylbenzoate 丨cas 181139-72-0 manufacturers, lwm tus neeg, Hoobkas
