Hangzhou Leap Chem Co., Ltd. yog ib qho ntawm cov kws tshaj lij thiab cov neeg muag khoom ntawm ethanol, 2-(3ar,4s,6r,6as)-6-5-amino-6-chloro-2-(propylthio)-4-pyrimidinylaminotetrahydro-2,2-dimethyl-4h-cyclopenta-1,3-dioxol-4-yloxy-761cas-China Txais tos rau kev lag luam wholesale kev cai ua cov khoom lag luam ntawm tus nqi sib tw los ntawm peb lub hoobkas. Rau cov khoom pheej yig dua, tiv tauj peb tam sim no.
Specifications
| Qhov tshwm sim | Dawb rau lub teeb liab dawb |
| Kev txheeb xyuas (IR) | Lub infrared absorption spectrum ntawm cov qauv sib raug rau cov khoom siv siv |
| 152-99 | 0.15% max |
| Max tsis paub ib qho impurity | 0.15% max |
| Tag nrho impurities | 1% max |
| Poob rau ziab | 2% max |
| Dej | 1.5% max |
| Enantiomer | 0.1% max |
| Residue ntawm ignition | 0.5% max |
| Assay (nyob rau hauv cov nqe lus ntawm anhydrous) | 98% mus rau 102% |
Daim ntawv thov
Cov tshuaj no feem ntau yog siv los ua ib qho tseem ceeb nruab nrab hauv kev tshawb fawb tshuaj tiv thaiv kab mob thiab kev loj hlob. Nws cov nucleoside complex-zoo li cov qauv ua rau nws tsim nyog rau kev sib txuas ntawm nucleoside analogues uas tuaj yeem cuam tshuam cov kab mob sib kis los ntawm kev tsom mus rau cov kab mob polymerases lossis cuam tshuam nrog nucleic acid synthesis. Nws yog siv rau hauv tshuaj chemistry los tsim thiab kho cov tshuaj tiv thaiv kab mob, tshwj xeeb tshaj yog rau cov kab mob RNA thiab DNA. Tsis tas li ntawd, qhov sib xyaw yog siv hauv kev tshawb fawb biochemical rau kev kawm txog kev sib cuam tshuam ntawm enzyme, prodrug cov tswv yim, thiab cov qauv-kev sib raug zoo hauv nucleoside-raws li cov neeg sib tw tshuaj. Nws kuj tseem ua lub tsev thaiv rau kev npaj cov hloov kho nucleotides thiab nucleoside derivatives rau kev tshuaj xyuas tshuaj.
Cov txiaj ntsig
Lub compound muaj ntau yam zoo vim nws cov functionalized heev thiab stereochemically txhais cov qauv. Nws ntau pawg reactive, suav nrog cov amino, chloro, thiab propylthio hloov pauv, tso cai rau kev xaiv tshuaj hloov pauv thiab derivatization, uas yog qhov tseem ceeb rau kev tsim cov tshuaj muaj zog thiab xaiv cov tshuaj tiv thaiv kab mob. Cov tetrahydrocyclopentane thiab dioxol moieties muab kev ruaj ntseg thiab rigidity, txhawb kev metabolic tsis kam thiab txhim kho cov khoom pharmacokinetic hauv cov khoom sib txuas. Tsis tas li ntawd, nws cov stereochemical precision ua kom muaj kev rov tsim dua tshiab hauv kev tshawb fawb hluavtaws thiab tshuaj, thaum lub nucleoside-zoo li lub hauv paus tswj kev koom ua ke rau hauv nucleic acid analogues rau kev ua haujlwm lom neeg.
Xaus
Ethanol, 2-(3aR,4S,6R,6aS)-6-(5-amino-6-chloro-2-(propylthio)-4-pyrimidinylamino)tetrahydro-2,2-dimethyl-4H-cyclopenta[1,3] dioxol muaj nuj nqis) hauv tshuaj intermediates nucleoside analogue synthesis. Nws cov ntawv thov hauv tshuaj chemistry thiab kev tshawb fawb biochemical, ua ke nrog cov txiaj ntsig xws li kev ruaj ntseg ntawm cov qauv, stereochemical precision, thiab ntau yam kev ua haujlwm, ua rau nws yog ib qho tseem ceeb hauv tsev thaiv kev tsim kho tshiab antiviral. Lub compound txuas ntxiv txhawb kev tsim kho tshiab hauv kev tsim tshuaj nucleoside thiab kev tshawb fawb tshuaj kho mob siab.
Cim npe nrov: ethanol, 2-(3ar,4s,6r,6as)-6-5-amino-6-chloro-2-(propylthio)-4-pyrimidinylaminotetrahydro-2,2-dimethyl-4h-cyclopenta-oxyyl-4,3 376608-74-1, Tuam Tshoj ethanol, 2-(3ar,4s,6r,6as)-6-5-amino-6-chloro-2-(propylthio)-4-pyrimidinylaminotetrahydro-2,2-dimethyl-4h-cyclopenta-1,3-dioxol-7-6-1. manufacturers, lwm tus neeg, Hoobkas
