Hangzhou Leap Chem Co., Ltd. yog ib qho ntawm cov tuam txhab tshaj lij thiab cov neeg muag khoom ntawm sn-1,2-dioctanoylglycerol丨cas 60514-48-9 hauv Suav teb. Txais tos rau kev lag luam wholesale kev cai ua cov khoom lag luam ntawm tus nqi sib tw los ntawm peb lub hoobkas. Rau cov khoom pheej yig dua, tiv tauj peb tam sim no.
Specifications
| Purity (¹H NMR) | 95% min |
| Qhov tshwm sim | Lub teeb daj oily kua |
Daim ntawv thov
sn-1,2-Dioctanoylglycerol yog dav siv los ua biochemical reagent nyob rau hauv cellular thiab molecular biology, tshwj xeeb tshaj yog raws li ib tug functional analog ntawm natural diacylglycerols (DAGs) uas koom nyob rau hauv intracellular signaling pathways. Hauv kev tshawb fawb ib puag ncig, nws ua haujlwm ua lub zog muaj zog ntawm cov protein kinase C (PKC), ua rau nws muaj txiaj ntsig rau kev kawm txog cov txheej txheem ntawm cov teeb liab hloov, kev qhia cov noob, daim nyias nyias, thiab kev sib txawv ntawm tes. Nws zoo- yam ntxwv ua haujlwm ua rau muaj kev tswj hwm kev txhawb nqa ntawm PKC- cov lus teb nyob rau hauv lub cev tiv thaiv kab mob, cov kab mob neuronal, thiab cov qauv endocrine. Cov tshuaj tseem siv tau rau hauv kev tshuaj ntsuam xyuas tshuaj los tshawb txog kev sib cuam tshuam ntawm cov neeg xa xov lipid thiab lawv cov hom phiaj protein, txhawb kev siv tshuaj tshawb nrhiav hauv oncology, o, metabolic ntshawv siab, thiab kev tshawb fawb plawv. Tshaj li cov kev tshawb fawb qhia, sn-1,2-Dioctanoylglycerol pom kev siv hauv daim nyias nyias biophysics, qhov uas nws ua raws li kev hloov pauv ntawm lipid bilayer lub koom haum, pab kev tshawb fawb rau hauv daim nyias nyias fluidity, vesicle fusion, thiab lipid-protein kev cuam tshuam. Nyob rau hauv enzymology, nws ua hauj lwm pab raws li ib tug substrate los yog siv compound rau lipase, kinase, thiab phospholipase assay, pab rau txoj kev loj hlob thiab optimization ntawm bioanalytical txoj kev. Nws cov xwm txheej amphiphilic thiab tswj acyl saw ntev kuj ua rau nws muaj txiaj ntsig zoo hauv kev tshawb fawb, suav nrog kev tshawb fawb txog emulsifiers, lipid xa tshuab, thiab bioactive lipid cov cab kuj tsim los txhim kho kev solubility thiab cellular uptake hauv kev sim formulations. Tsis tas li ntawd, qhov sib xyaw ua haujlwm qee zaus hauv kev tshawb nrhiav cov metabolism hauv kev tshawb nrhiav glyceride ua, lipid turnover, thiab mitochondrial fatty-acid tuav, muab kev nkag siab rau hauv kev tswj cov kab mob metabolic nyob rau hauv physiological thiab pathological mob.
Cov txiaj ntsig
sn-1,2-Dioctanoylglycerol muaj ntau yam zoo rau cov kws tshawb fawb thoob plaws cov kev kawm lom neeg, tshuaj lom neeg, thiab tshuaj tshuaj. Ib qho ntawm nws cov txiaj ntsig tseem ceeb yog nws qhov kev kwv yees tau thiab rov ua dua tshiab raws li PKC activator, tso cai rau cov kws tshawb fawb los txhawb cov lus teb ntawm tes nrog qhov raug thiab sib xws. Piv nrog cov endogenous DAGs, uas tuaj yeem nthuav tawm kev hloov pauv sai thiab cov qauv sib txawv, cov khoom siv hluavtaws no muab kev ruaj ntseg zoo dua thiab kev tswj hwm kev ua haujlwm, ua kom muaj kev txhim kho kev sim ntau dua. Nws kuj luv yim yim-carbon acyl chains txhim kho solubility thiab membrane incorporation, tso cai rau cov compound kom diffuse zoo nyob rau hauv cell{14}}raws li systems thiab tsim sai, zoo li lom los. Qhov kev tswj tau hydrophobicity no kuj yooj yim rau kev npaj thiab tuav, txo qhov kev xav tau ntawm cov tshuab hnyav hnyav. Raws li cov ntaub ntawv siv, sn-1,2-Dioctanoylglycerol yog qhov tseem ceeb rau kev ua qauv bioassays, txhim kho qhov zoo, sib piv, thiab rov tsim dua ntawm cov ntaub ntawv tshawb fawb. Nws txhais tau hais tias stereochemistry tso cai rau lub hom phiaj ua kom muaj kev taw qhia txoj hauv kev nrog tsawg kawg nkaus -cov phiaj xwm kev sib cuam tshuam, txhawb nqa cov kev tshawb fawb txog kev siv tshuab uas xav tau kev ua haujlwm siab. Hauv kev tshawb fawb hauv daim nyias nyias, nws cov khoom tunable bilayer - modulating zog tso cai rau cov neeg tshawb nrhiav los kho cov lipid muaj pes tsawg leeg los ua kom lub cev muaj zog lossis kev ntxhov siab, ua kom muaj kev nkag siab zoo dua rau hauv daim nyias nyias thiab cov txheej txheem tswj hwm lipid-dependent. Rau kev txhim kho tshuaj, qhov sib xyaw ua ke muaj peev xwm ua rau cov neeg xa xov xwm endogenous pab cov neeg tshawb nrhiav qauv kab mob ntsig txog txoj hauv kev, ua rau nws muaj txiaj ntsig zoo rau kev tshuaj ntsuam xyuas cov qauv ntawm PKC thiab cov proteins uas muaj feem xyuam. Hauv kev siv cov kev tshawb fawb txog kev tsim, nws cov amphiphilic profile txhawb kev txhim kho kev tawg, ua rau nws tsim nyog rau kev soj ntsuam lipid-raws li kev xa tsheb thiab nkag siab txog lawv cov kev cuam tshuam nrog cov kab mob lom.
Xaus
sn-1,2-Dioctanoylglycerol yog ntau yam thiab muaj txiaj ntsig zoo uas ua lub luag haujlwm tseem ceeb hauv biochemical niaj hnub thiab lub neej- kev tshawb fawb txog kev tshawb fawb. Nws cov txiaj ntsig tseem ceeb yog los ntawm nws txoj haujlwm ua haujlwm ruaj khov, zoo- txhais DAG analog muaj peev xwm xaiv cov protein kinase C, ua kom muaj siab - kev tshawb xyuas qhov tseeb rau hauv xov tooj ntawm tes. Nws cov khoom kuj tseem txhawb cov ntawv thov hauv daim nyias nyias biophysics, enzymology, kev tshawb fawb lipid metabolism, thiab kev sim kev tsim kho. Cov txiaj ntsig ntawm qhov sib xyaw ua ke suav nrog kev ua kom muaj roj ntsha rov ua dua tshiab, cov yam ntxwv yooj yim solubility, cov ntsiab lus stereochemical, thiab kev sib raug zoo nrog cov xov tooj ntawm tes{13}}raws li kev tshuaj ntsuam biochemical. Cov txiaj ntsig no ua rau sn-1,2-Dioctanoylglycerol yog qhov kev xaiv zoo thiab txhim khu kev qha rau cov kws tshawb fawb nrhiav kom nkag siab txog cov txheej txheem kev tswj hwm lipid-mediated lossis tsim PKC-txog cov tswv yim kho mob.
Cim npe nrov: sn-1,2-dioctanoylglycerol 丨cas 60514-48-9, Tuam Tshoj sn-1,2-dioctanoylglycerol丨cas 60514-48-9 manufacturers, lwm tus neeg, Hoobkas
