ESTRAMustine phosphate sodium 丨 cas 52205-73-9

ESTRAMustine ntsev sodium 丨 cas 52205-73-9 Puas muaj kev siv tshuaj kho mob tshwj xeeb tau tsim los rau cov qog nqaij hlav. Nws muab cov tshuaj hormonal ntawm estrogen nrog lub cytotoxic nyhuv ntawm alkylating tus neeg sawv cev, muab ib txhais tau ob txhais cov kev ua.

1. Kev kho mob ntawm prostate cancer
Siv cov neeg mob pallphate los sis cov tshuaj tiv thaiv kab mob praltative lossis cov tshuaj tiv thaiv prostingatic lossis cov hormartection-refrace-resistant prostate cancer.
● Mechanism: nws cuam tshuam microuvubuity muaj nuj nqi, ua rau kev txwv ntawm tes thiab qog cell agoptosis.
● Cov yam ntxwv Hormaty: Estradiol Moiety muab cov qib kev andrression, uas tau txais txiaj ntsig hauv prostate cancer uas tsav los ntawm androgens.

2. CyTostatic Tus Neeg Sawv Cev Hauv Oncology
Cov tshuaj tiv thaiv: Estramustine cuam tshuam nrog microtubule hluav taws xob nrawm nrawm, yog li ua haujlwm raws li microlotubuel. Tsis zoo li ib txwm nitrogen lithards, nws cytotoxicity yog ntau rau ntawm mitotic inhibition dua DNA Alkylation.
Kev kho kev sib xyaw ua ke: feem ntau siv ua ke nrog lwm cov anticancer sawv cev xws li Diletaxel lossis Vinblastine los txhim kho kev ua tau zoo thiab tswj kev ua haujlwm.

3. Tshawb xyuas cov ntawv thov
● Kev tshawb fawb txog biology: siv hauv kev tshawb fawb txog qib thiab hauv cov qauv vitro mus tshawb fawb:
OmicRotubule-txuam protein zog
Ohormone-teb cov qog kev loj hlob
Olehe Colleplay ntawm Kev Kho Mob Txoj Kev Kho Mob Ntawm Cov Tshuaj Kho Mob
● Kev xaiv tshuab Kev tshawb fawb tshuab

1. Dua lil me ntsis kev ua
● Txuas cov tshuaj estrogen ntawm kev loj hlob ntawm tes nrog microTubule Inhibition, ua rau nws tshwj xeeb rau cov kws kho mob.
● Txo qhov kev xav tau ntawm cov hormonal cais thiab cov neeg sawv cev cyotoxic.
2. Xaiv cov phiaj xwm ntawm prostate cancer hlwb
Antramustine nyiam ua kom pom tseeb hauv cov nqaij mos thiab prostatic cov qog, ua rau cov kev ua si tshwj xeeb thiab kev txo qis-hom phiaj tshuaj lom rau cov tsis xaiv cytotoxins.
3. Qhov ncauj tswj hwm
Part ● Yuav tuaj yeem muab cov lus qhia txog tus neeg mob, muab qhov xav tau qhov xav tau rau cov kev tsis muaj peev xwm ntawm palliating chaw.
4. Synergistic hauv kev kho kev kho
● Qhia cov teebmeem kev cuam tshuam thaum siv nrog lwm cov tshuaj kho kom zoo li cov neeg ntiav thiab Platinum-raws li kev muaj sia nyob rau hauv cov neeg mob theem siab-theem.

Tag
Estramustine ntsev sodium 丨 cas 52205-73-9 yog tus neeg sawv cev tshwj xeeb siv rau kev kho mob prostate. Nws qhov tshwj xeeb tsim-sib xyaw hluav taws xob ib qho hluav taws xob ib qho tshuaj tua hluav taws xob nrog lub alkylating tus neeg sawv cev-muaj qhov tshwj xeeb tshaj yog hauv cov tshuaj tiv thaiv cov tshuaj hormones. Nrog cov txiaj ntsig zoo li cov xaib uas tsis muaj qhov tseeb, thiab microrotuble cuam tshuam tseem muaj cov khoom siv rau hauv Atcologte tseem nyob hauv tus kws kho mob hauv Atcologte.