Hangzhou Leap Chem Co., Ltd. yog ib qho ntawm cov kws tshaj lij thiab cov neeg muag khoom ntawm pregabalin 丨cas 148553-50-8 hauv Suav teb. Txais tos rau kev lag luam wholesale kev cai ua cov khoom lag luam ntawm tus nqi sib tw los ntawm peb lub hoobkas. Rau cov khoom pheej yig dua, tiv tauj peb tam sim no.
Specifications
| Qib | USP Qib |
| Qhov tshwm sim | Dawb mus yuav luag dawb crystalline hmoov |
| Kev ntsuam xyuas (HPLC) | 98.0 ~ 102.0% (lub hauv paus qhuav) |
| Kev txheeb xyuas (IR) | IR spectrum yog ua raws li tus qauv siv |
| Kev txheeb xyuas (HPLC) | Lub sijhawm khaws cia ntawm lub ncov loj ntawm cov qauv kev daws teeb meem sib raug rau cov qauv kev daws teeb meem, raws li tau txais hauv Assay |
| Poob rau ziab | 0.5% max |
| Residue ntawm ignition | 0.1% max |
| Chloride | 0.1% max |
| Lwm yam tshuaj (HPLC) - Isobutylglutaric acid | 0.15% max |
| Lwm yam tshuaj (HPLC) - Isobutylglutammonamide | 0.15% max |
| Cov tshuaj muaj feem xyuam (HPLC) - USP muaj feem xyuam nrog C | 0.15% max |
| Tej yam tsis meej tsis meej | 0.10% max |
| Tag nrho impurity | 0.5% max |
| Isomer (HPLC) - USP muaj feem xyuam nrog A | 0.15% max |
| Residual solvents (GC) - 2-Propanol | 5000 ppm max |
| Residual solvents (GC) - Iso-butanol | 5000 ppm max |
Daim ntawv thov
Pregabalin yog ib qho tshuaj siv dav siv tshuaj feem ntau qhia rau kev tswj cov mob neuropathic, qaug dab peg, thiab qee yam kev ntxhov siab. Nws yog feem ntau sau rau cov mob xws li mob ntshav qab zib peripheral neuropathy, postherpetic neuralgia, fibromyalgia, thiab raws li kev kho mob rau ib nrab - pib qaug dab peg. Pregabalin kuj tau kawm thiab siv hauv kev kho mob ntawm kev ntxhov siab dav dav vim nws cov teebmeem modulatory ntawm cov teeb liab neuronal. Hauv kev tshawb fawb thiab kev tsim tshuaj, pregabalin ua haujlwm tseem ceeb hauv kev siv tshuaj thiab cov khoom xyaw nquag rau kev tsim kho, kev tshawb fawb bioequivalence, thiab kev tswj kom zoo. Nws cov ntaub ntawv pharmacological zoo ib yam ua rau nws yog ib qho tseem ceeb hauv kev kho mob thiab kev txhim kho tshuaj.
Cov txiaj ntsig
Pregabalin muaj ntau qhov zoo vim nws qhov zoo -txoj kev txiav txim siab thiab kev ua siab ntev. Nws khi rau 2δ subunit ntawm voltage-gated calcium channels hauv nruab nrab paj hlwb, txo cov kev tso tawm ntawm excitatory neurotransmitters thiab li no alleviating mob thiab qaug dab peg. Cov khoom sib xyaw ua kom pom kev muaj peev xwm ntawm qhov ncauj siab, kev kwv yees cov tshuaj pharmacokinetics, thiab kev sib cuam tshuam ntawm cov tshuaj yeeb-tshuaj tsawg tsawg, ua kom yooj yim dua thiab kev tswj tus neeg mob. Pregabalin feem ntau zam tau zoo, nrog rau qhov pib ua haujlwm sai thiab muaj txiaj ntsig zoo sib xws hauv ntau qhov kev qhia. Nws cov tshuaj lom neeg ruaj khov thiab kev ua tau zoo dua qub txhawb kev txhim khu kev lag luam tshuaj thiab loj - teev ntau lawm.
Xaus
Pregabalin yog tus kws kho mob tseem ceeb nrog kev siv dav hauv kev kho mob neuropathic mob, qaug dab peg, thiab kev ntxhov siab - cuam tshuam txog kev puas tsuaj. Nws cov txiaj ntsig, suav nrog cov phiaj xwm kev hloov kho neuronal, muaj bioavailability siab, kev kwv yees tshuaj pharmacokinetics, thiab kev ua siab ntev, ua rau nws yog lub hauv paus tseem ceeb hauv kev kho mob hlwb niaj hnub thiab kev kho mob. Cov tshuaj txuas ntxiv ua lub luag haujlwm tseem ceeb hauv kev kho mob thiab kev tshawb fawb tshuaj.
Cim npe nrov: Pregabalin 丨cas 148553-50-8, Tuam Tshoj pregabalin 丨cas 148553-50-8 manufacturers, lwm tus neeg, Hoobkas
