Cov lus qhia
| Kev tshwm sim | Dawb rau tawm - hmoov dawb |
| Assisy (ntawm anhydroudous hauv paus) | 98.0% rau 102.0% |
| So | ph {- Nyob ntawm solubility nyob rau aqueous media; Dawb soluble nyob rau hauv duethyl sulfoxide |
| Daim qhia npe | IR: Kev nqus spectrum concordant nrog kev sim cov qauv HPLC: Spectrum Concordant nrog Cov Tshuaj Txheem |
| Polymorphic Daim Ntawv | Ua kuv |
| Ywg dej | 1.0% max |
| Residue ntawm ignition | 0.1% Max |
| Cov hlau hnyav | 20 PPM Max |
| Particle loj tso tawm (D90) | 20 μm Max |
| Khoom siv tsev | 0.15% Max |
| Lwm yam tshuaj | Lwm yam impurity: 0.1% Max Tag nrho cov impurities: 1.0% max |
| Residual cov kuab tshuaj | Dichhloromethane: 0.06% Max Ethanhol: 0.5% Max Acetone: 0.5% Max Ethyl acetate: 0.5% Max n - heptane: 0.5% max |
| Microbial txwv | Tag nrho cov aerobic microbial suav: 1000 CFU / G Max Tag nrho cov poov xab thiab pwm: 100 cfu / g max Escherichia coli: Tsis tuaj / g |
Cov Ntaub Ntawv Thauj
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Chaw ua uas tsis tau haus |
Kev qhia tshwj xeeb |
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UN NUM |
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Hom |
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Cov Pab Pawg |
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Hs code |
3004909099 |
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Ruaj khov & rov ua |
Cov khoom lag luam ruaj khov nyob rau hauv cov qauv ambient ambient. |
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Chaw ntim khoom |
Khaws kaw kom nruj. Khaws raws li cov ntaub ntawv teev rau ntawm cov khoom ntxig. |
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Mob kom tsis txhob |
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Lub thawv |
Cov ntaub ntawv raug
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Chaw ua uas tsis tau haus |
Kev qhia tshwj xeeb |
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Lub peev xwm |
20kg / hli |
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Hov ntau |
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Lub teb chaws tseem ceeb |
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Peev Xwm / Batch |
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Paub lawm |
Ntau lawm txij xyoo 2018 |
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Ntxiv rau |
Cov Ntawv Thov
Acalabrutinib yog ib tug xaiv heev coluton's tyrosine Kinase (BTK) Inhibitor feem ntau siv nyob rau hauv kev kho mob hematological malignancies. Nws tau tsim los ua lub hom phiaj kho rau cov mob xws li Mantle Cell Lymphoroma (McL), mob Lymmocytic Lymphoroma (SLL). Los ntawm irreveribly khi rau btk, ib qho tseem ceeb enzyme hauv b} cell recwor kos npe rau cov kab ke uas tsav malignant b {}} kev sib tw ntawm tes thiab muaj sia nyob. Hauv kev tshawb nrhiav hauv tsev kho mob, nws feem ntau ua raws li kev ua haujlwm monotherapy lossis ua ke nrog lwm tus neeg sawv ntxov, nthuav nws cov tshuaj kho. Tshaj rau sab hauv kev kawm, txuas ntxiv tshawb fawb tau tshawb txog nws lub peev xwm hauv autoimmune thiab mob tsis txaus ntseeg, muab BTK lub luag haujlwm tiv thaiv kev tiv thaiv kev ua haujlwm ntawm tes. Nws xaiv inhibition profile ua rau nws yog ib qho kev siv tshuaj tseem ceeb rau kev nce qib tshuaj kho tswv yim hauv hematology thiab kev txhaj tshuaj tiv thaiv.
Cov txiaj ntsig
Cov txiaj ntsig ntawm Acalabrutinib nyob rau hauv nws cov kev xaiv siab, kev ua tau zoo, thiab txhim kho kev tsim kho piv rau btk ua ntej btk inhibitors. Los ntawm kev sib tw tiv thaiv btk nrog tsawg kawg ntawm- hom kev pheej hmoo, nws txo qhov kev pheej hmoo ntawm kev cuam tshuam loj uas feem ntau cuam tshuam nrog kev cuam tshuam dav. Qhov no ua kom tus neeg mob ua raws thiab ntev - lub sij hawm kho cov txiaj ntsim tau tshwm sim. Cov kev tshawb fawb soj ntsuam tau pom nws txoj kev ua tau zoo hauv kev tswj b {{5 5}} cov lus teb ruaj khov, nrog cov lus teb kev nyab xeeb nyab xeeb. Tsis tas li ntawd, nws lub peev xwm los ua ke nrog lwm cov kev kho mob lossis tshuaj tiv thaiv kab mob nthuav dav nws cov nqi hluav taws xob nthuav dav. Nws qhov ncauj ntawm qhov ncauj thiab cov koob tshuaj tiv thaiv yooj yim kuj ua rau nws nkag tau rau ntev- kev tswj hwm ntawm cov xwm txheej ntev. Zuag qhia tag nrho, acalabrutinib Piv txwv tshiab niaj hnub no nyob rau hauv precision atcology los ntawm kev tswj cov kab mob thiab muaj txiaj ntsig zoo ntawm lub neej.
Tag
ACALABRUTINIB (CAS 1420477 {{-}}}}}}}}}}}} malignor thiab tab tom tshawb fawb rau cov ntawv thov dav dav hauv kev tiv thaiv kev tiv thaiv kev tiv thaiv kev tiv thaiv kev tiv thaiv kev tiv thaiv cov tshuaj tiv thaiv kab mob B-Cell Nws cov kev ua tshuab ntawm kev nqis tes ua, kev xaiv siab, thiab kho mob tau ua rau nws tseem ceeb ntawm kev kho cancer. Nrog cov txiaj ntsig suav nrog cov lus teb tsis tu ncua, thiab kev coj kom haum rau cov kev sib xyaw ua ke, Acalabrutinib sawv cev rau kev nce qib tseem ceeb hauv cov tshuaj precision. Raws li kev tshawb fawb txuas ntxiv, nws zoo li yuav nthuav nws lub luag haujlwm hauv kev kho cov qog nqaij hlav hematologic, cov kev tiv thaiv kab mob, txuas ntxiv rau cov kev kho mob niaj hnub no.
Cim npe nrov: Acalabrutinib 丨 CAS CAS CAS 1420477-60-6, Tuam Tshoj Acalabrutinib 丨 Cas 1420477-60-6 tuam ntxhab, cov chaw muag khoom, Hoobkas
