Cov lus qhia tshwj xeeb ntawm Metronidazole 丨 443-48-1
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Ntiag tug |
Kev qhia tshwj xeeb |
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Teem nqi |
USP43 |
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Daim qhia npe |
IR: kev sib piv nrog metronidazole crs |
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HPLC |
Lub sijhawm khaws cia ntawm cov chromatogram ntawm cov assay npaj sib raug rau qhov ntawd hauv cov qauv kev npaj, raws li tau txais hauv cov assay |
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Poob rau ziab |
{{0 {}}. 5% Max |
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So |
Soluble me ntsis hauv dej, acetone, dej cawv, thiab methylene chloride |
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Residue ntawm ignition |
0. 1% Max |
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Cov hlau hnyav |
20 PPM Max |
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Lwm yam tshuaj |
Tinidazole Related A: {0. 1% Max |
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Tag nrho cov impurities |
{{0 {}}. 2% Max |
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Organic seem (Ethylene Oxide) |
1 ppm max |
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Assay (ntawm qhuav hauv paus) |
99.0% - 101.0% C₆H₉N₃O₃ |
Lub hauv paus rau phau ntawv
Metronidazole {443-48-1 yog cov tshuaj tua kab mob thiab cov tshuaj tua kab mob feem ntau siv cov kab mob, suav nrog cov kab mob thiab protozoa. Nws yog dav siv hauv kev kho mob tshuaj vim nws cov hauj lwm zoo hauv kev kho cov kab mob hauv cov khoom sib txawv, nrog rau nws lub peev xwm los nkag rau cov nqaij mos rau nws lub peev xwm.
Mechanism ntawm Kev Ua
Metronidazole {{443-48-1 ua haujlwm los ntawm kev cuam tshuam rau DNNture DNNture Synthesis nyob microbial. Nws yog txo rau hauv lub xov tooj ntawm tes, qhov uas Nitro Group tau txais los ntawm Anaerobic tej yam ntawm qee yam kab mob thiab protozoal kis tau. Qhov kev txo ntawm Nitro Group tsim cov kev cuam tshuam txog DNA, ua rau kev tuag cell tuag. Cov tshuaj yog siv tau tshwj xeeb rau cov kab mob anaerobic thiab protozoa, vim tias lawv muaj peev xwm txo metronidazole rau nws daim ntawv nquag.
Siv thiab kev siv ntawm metronidazole 丨 443-48-1
Metrnidazle tau siv dav siv t kho cov kab mob tshwm sim los ntawm cov kab mob anaerbic thiab prtza. CMMN cov ntawv thov muaj xws li:
1.Txoj kev sib kis tau:
Anaerbic cov kab ke: Metrnidazle: Metrnidazle: {0}} yog fent affibed t kho cov kab mob tshwm sim los ntawm anaGen-deprived xaim. Cov kab mob no suav nrog CNDitins xws li:
Intra-abdlminal sib txig sib kis (piv txwv li, aniticitis, diverticulitis)
● Pelvic cov kab ke (piv txwv li, pelvic inflammalry)
● Abscesses nyob rau hauv varius rgans (piv txwv li, daim siab tsis zoo)
Daim tawv thiab SFT DUMUM NQUS TAU: METRNIDAZLE muaj txiaj ntsig zoo hauv kev kho cov tawv nqaij kis tau los ntawm anaerbes, xws li cellulitis r necrtizing fasciitis.
Cov sib kis tau: Nws yog siv los kho cov hniav sib kis hniav thiab kab mob peridntal los ntawm cov kab mob ntawm cov kab mob anaerbic, suav nrog gingivitis thiab mob peridntitis.
2.Qhov cov kis tau:
Giardiasis: Metrnidazle 丨 {443-48-1} yog thawj-Line Kev Kho Mob Fr Giardia, uas yog tus cwj pwm los ntawm kev zwj, mob siab, thiab malabstrptin.
Amebiasis: Metrnidazle yog siv t Ua kom muaj kev sib txig tshwm sim los ntawm Contamba Cov Neeg Koom Tes, uas ua rau Amebic dysenty thiab tuaj yeem ua T Liv lub siab.
Trichmniasis: Metrnidazle yog cov tshuaj f chicmnas Vaginite Vaginite Vaginalis, ib tug prtzan parasite respnsible fr trichmniasis, muaj kev sib deev kis.
Balantidiasis: ib qho tsawg dua cmmn kis tau los ntawm Balantidium cli, uas metrnidazle tuaj yeem als kho.
3.HelicBacter Pylri Eradicatin:
Metrnidazle {443-48-1 yog smettimes siv los ua ib feem
4.pical siv:
Metrnidazle yog als muaj nyob rau hauv tpical frmulatins (piv txwv li cov tshuaj pleev xim r
5.Xyurgical Prphylaxis:
Tej zaum nws yuav siv nyob rau hauv prpphylaxis fr qee yam kev phais mob, tshwj xeeb yog therlving lub gastrintestinal laij teb r catherbic cov kev sib kis.
Cov txiaj ntsig thiab txiaj ntsig zoo ntawm metronidazole 丨 443-48-1
1.Brad spectrum kev ua:
Metrnidazle 丨 443-48-1}} Pib tawm tsam ntau yam F Anaerbic kab mob sib kis hauv varius reg reg tshuab.
2. CEEB TOOM HAUV CHAGE DUAB:
Metrnidazle yog zoo-Absrbed thiab tuaj yeem nkag mus rau cov ntaub so ntswg yooj yim, nrog rau lub hlwb, uas yog qhov tseem ceeb fr ua kev kho kom sib txig sib kis.
3.GD Ral BiaVailability:
Thaum coj Rally, metrnidazle muaj gd biaadailability (abut 90%), Allws nws t ua tau zoo hauv kev kho bth lcalized thiab system sib kis.
4.pical cov ntawv thov:
Qhov muaj f tpical Metrnidazle frmulatins Allw Flu Kev tswj cov tawv nqaij cnditins zoo li Rsacea, nrog kev mob tshwm sim rsacea, nrog txo cov kev phiv.
5.CMBINATIN THEEM:
Metrnidazle 丨 443-48-1}} yog ft antepinatin nrog rau cov ilegrtzal muaj zog hauv cnditins zoo li HelicBacter Pylri Eradicatin.
Tag
Metronidazole {443-48-1 yog cov tshuaj tiv thaiv dav dav thiab antiprotozoal tus neeg sawv cev uas muaj txiaj ntsig los ntawm cov kab mob anaerobic thiab protozoa. Nws lub peev xwm mus rau cov ntaub so ntswg nkag mus zoo, ua ke nrog nws txoj kev kho mob zoo, suav nrog Giardiasis, Amebibonias, thiab Anaerobic kab mob. Nws yog feem ntau ua zam txim rau tab sis yuav ua rau cov kev mob tshwm sim xws li kev mob plab zom mov, neuralological tshwm sim, thiab kev ua xua. Zoo li tag nrho cov tshuaj, nws yuav tsum ua tib zoo saib, tshwj xeeb tshaj yog thaum siv sijhawm ntev lossis hauv cov neeg mob uas muaj mob siab. Txawm hais tias cov kev txhawj xeeb no, nws cov txiaj ntsig los kho qee yam kab mob nyob deb qhov txaus ntshai, ua rau nws muaj txiaj ntsig zoo hauv cov khoom siv niaj hnub.
Cim npe nrov: metronidazole} 443-48-1}}
