Cov lus qhia tshwj xeeb ntawm Dintomycin yog 103060-53-3
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Zog: |
Daj lossis daj ntseg daj amorphous hmoov |
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Assisy (ntawm lub anhydrous hauv paus): |
93.0% min |
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Daim qhia npe: |
HPLC, IR, UV |
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Kev sib hloov tshwj xeeb: |
{{0 {}}℃rau +25 degree |
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Ph: |
3.0 rau 5.0 |
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Residue ntawm ignition: |
4.0% Max |
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Anhydro-Daptomycin: |
3.5% max |
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-Imus: |
2.0% Max |
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Lactone hydrolysis khoom: |
1.5% Max |
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Impurity Rs-2: |
0.5% max |
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Lwm yam impurity: |
0.15% Max |
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Tag nrho cov impurities: |
8.0% Max |
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Residual Orgicic Cov kuab tshuaj: |
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Ethanhol: |
0.5% max |
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Isopropanol: |
0.5% max |
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Cov hlau hnyav: |
20 PPM Max |
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Dej: |
10.0% Max |
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Bacterial endotoxin: |
0.5 EU / MG Max |
Cov ntaub ntawv thauj ntawm Dintomycin yog li 103060-53-3
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Chaw ua uas tsis tau haus |
Kev qhia tshwj xeeb |
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UN NUM |
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Hom |
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Cov Pab Pawg |
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Hs code |
3004209099999 |
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Ruaj khov & rov ua |
Cov khoom lag luam ruaj khov nyob rau hauv cov qauv ambient ambient. |
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Chaw ntim khoom |
Nruj nreem kaw. . -20 degree |
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Mob kom tsis txhob |
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Lub thawv |
Cov ntaub ntawv kev tsim khoom ntawm Daptomycin yog 103060-53-3
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Chaw ua uas tsis tau haus |
Kev qhia tshwj xeeb |
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Lub peev xwm |
100kg / hli |
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Hov ntau |
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Lub teb chaws tseem ceeb |
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Peev Xwm / Batch |
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Paub lawm |
Ntau lawm txij xyoo 2011 |
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Ntxiv rau |
Lub ntsiab
Daptomycin 丨 CAS 103060-53-3 yog ib qho muab tau losCOLBIC Lipopeptide Tshuaj Ntsigtsim los ntawmStreptoryces RoseosporusCov. Nws muaj ib qho tshwj xeeb mechanism ntawm kev ua thiab paub rau nws txoj haujlwm muaj zog tiv thaivGram-zoo tus kab mob, suav nrog multidrug-resistant leeg.
Cov Ntawv Thov
1. Cov tshuaj tiv thaiv tshuaj tua kab mob
Kev Siv Thawj:Kev Kho MobMuaj Kab Mob Loj Tshaj Plaws, suav nrog:
Methicillin-resistantStaphylococcus aureus(MRSA)
VANCOMONCIN-RESISTANTEnterococcus faecium(VRE)
StreptococcusSPP., suav nrog cov tshuaj tiv thaiv tshuaj tiv thaiv
FDA-Pom Zoo Qhia:
Cov tawv nqaij uas nyuaj thiab tawv nqaij sib kis (CSSSIS)
Staphylococcus aureusBacteremia, suav nrog txoj cai sib tshuam tas li expocarditis
2. Tsev kho mob thiab kev saib xyuas kev saib xyuas
Ua haujlwm hauvTsev Kho MobRau kev tswj tus mob tuag taus lub neej, tshwj xeeb tshaj yog thaum lwm cov tshuaj tua kab mob tsis tuaj yeem.
Siv tawm-daim ntawv lo rau Osteomyelitis, thiab kev kis mob hauv nruab nrab ntawm tus kws kho mob.
3. Tshawb xyuas cov ntawv thov
Siv nyob rau hauvCov kev tshawb nrhiav tshuaj tiv thaiv kab mob, pab cov kws tshawb nrhiav nkag siab tias cov kab mob yoog tau zoo li cas cov membrane-cov neeg sawv cev.
Kawm nyob rau hauv cov kws muag tshuaj cov khw muag tshuaj thiab cov qauv siv hluav taws xob los ua kom ua kom cov khoom siv hluav taws xob thiab txhim kho cov txiaj ntsig kho kom zoo.
Cov txiaj ntsig
1. Cim kev cai ntawm kev nqis tes ua
Membrane-hom tshuaj tiv thaiv kab mob:Daptomycin 丨 CAS 103060-53-3 INCERAGING rau hauv cov kab mob ntawm cov kab mob ntawm cov calcium-nqi yam, ua raumembrane depolarization thiab cell tuagtsis muaj lysis.
Qhov kev siv tshuab no txawv ntawm cov tshuaj tua kab mob thiab pab txoNtoo khaub lig-resistance.
2. Lub zog tiv thaiv cov kab mob resistant
Zoo heev tawm tsamNtau cov yeeb tshuaj tiv thaiv gram-zoo muaj txiaj ntsig, suav nrog MRSA thiab VRE, uas yog cov muaj ntau zuj zus hauv tsev kho mob-nrhiav tau.
3. Cov nqaij ntshiv
Kev ua yeeb yamCov txiaj ntsig sai li said, uas yog qhov zoo dua nyob rau hauv kis mob mob thiab sepsis qhov twg cov kab mob sai yog qhov tseem ceeb.
4. Tus ntoo khaub lig qis
Txij li nws lub hom phiaj cov kab mob memcbrane, Dintomycin feem ntau tseem nyob tau qhov twg -lactams, glycopeptides, thiab lwm chav kawm tau ua tsis tiav.
5. Tsawg txoj kev pheej hmoo ntawm Immunogenicity
Raws li tsis yog-glycopeptide, Daptonomycin muaj aTxo qhov ua rau muaj kev fab tshuaj tsis haumpiv rau penicillins lossis cepharosporins.
Tag
Daptomycin 丨 CAS 103060-53-3 yog ahaib, cov tshuaj khib nyiab lipopeptideSiv feem ntau rau cov kab mob gram hnyav, suav nrog cov tshwm sim los ntawm MRSA thiab VRE. Nws hom tshiab ntawm kev ua, kev ua haujlwm sai sai, thiab kev tiv thaiv ntau yam ntawm cov tshuaj tua kab mob tseem ceeb, tshwj xeeb hauv kev saib xyuas mob hnyav thiab ib cheeb tsam hauv tsev kho mob.
Cim npe nrov: Daptomycin 丨 CAS 103060-53-3, Tuam Tshoj Dintomycin 丨 CAS 103060-53-3 Cov Chaw Tsim Tshuaj, Chaw Tsim Tshuaj, Hoobkas
