Hangzhou Leap Chem Co., Ltd. yog ib qho ntawm cov tuam txhab tshaj lij thiab cov neeg muag khoom ntawm carbidopa monohydrate 丨cas 38821-49-7 hauv Suav teb. Txais tos rau kev lag luam wholesale kev cai ua cov khoom lag luam ntawm tus nqi sib tw los ntawm peb lub hoobkas. Rau cov khoom pheej yig dua, tiv tauj peb tam sim no.
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Specifications
| Qib | USP43 qib |
| Qhov tshwm sim | Dawb los yog creamy dawb hmoov, tsw ntxhiab los yog xyaum tsis muaj ntxhiab |
| Assay | 98.0% rau 102.0% |
| Solubility | me ntsis soluble hauv dej, dawb soluble hauv 3N hydrochloride acid; me ntsis soluble hauv methanol; xyaum insoluble hauv cawv, acetone, chloroform, thiab ether |
| Kev txheeb xyuas | A: IR: Sab nraud lub teeb nqus spectrum ntawm cov tshuaj ntsuam xyuas magenta yuav tsum ua raws li kev siv spectrum B: Assay: RT: Lub sijhawm khaws cia ntawm lub ncov tseem ceeb yuav tsum ua raws li cov ntaub ntawv siv |
| Ignition residue | 0.1% max |
| Carbidopa muaj feem xyuam nrog A | 0.5% max |
| Tag nrho impurities | 1.0% max |
| Lwm yam impurity | 0.1% max |
| Kev sib hloov tshwj xeeb | -21.0 ° C ~ -23.5 ° C |
| Poob rau ziab | 6.9 ~ 7.9% |
| Methyldopa | 0.5% max |
| Methanol | 3000 ppm max |
| 2-propanol | 5000 ppm max |
| Chloroform | 60 ppm max |
| Benzene | 2 ppm max |
| Toluene | 890 ppm max |
| Cyclhexanone | 20 ppm max |
Daim ntawv thov
Carbidopa Monohydrate feem ntau yog siv los kho kev sib xyaw nrog levodopa rau kev tswj hwm tus kab mob Parkinson thiab cuam tshuam txog kev txav mus los. Hauv cov neeg mob Parkinson, levodopa hloov mus rau dopamine nyob rau hauv lub hlwb, uas pab txo cov tsos mob xws li tshee, rigidity, thiab bradykinesia. Carbidopa inhibits peripheral decarboxylation ntawm levodopa, kom ntseeg tau tias ntau ntawm cov tshuaj levodopa nce mus txog lub hauv paus paj hlwb. Tshaj li Parkinson's, Carbidopa Monohydrate pom daim ntawv thov hauv kev tshawb fawb chaw rau kev tsim cov qauv uas txhim kho bioavailability thiab txo cov kev mob tshwm sim ntawm kev kho dopaminergic. Nws muaj nyob rau hauv cov tshuaj sib xyaw ua ke tso cai rau kev siv tshuaj kho kom zoo, txhim kho kev ua raws li tus neeg mob, thiab tshawb nrhiav txuas ntxiv - tso tawm cov qauv rau kev tswj cov tsos mob.
Cov txiaj ntsig
Cov txiaj ntsig tseem ceeb ntawm Carbidopa Monohydrate yog nyob rau hauv nws lub peev xwm los ua kom cov txiaj ntsig ntawm levodopa txoj kev kho mob thaum txo qis cov kev mob tshwm sim hauv peripheral xws li xeev siab, ntuav, thiab mob plawv. Los ntawm kev tiv thaiv kev hloov ntxov ntxov ntawm levodopa rau hauv dopamine sab nraum lub hlwb, Carbidopa txo cov koob tshuaj ntawm levodopa, yog li txhim kho kev nyab xeeb thiab ua kom ntev. Qhov kev sib koom ua ke no ua rau muaj kev tswj xyuas cov tsos mob zoo sib xws, kev ua haujlwm ntawm lub cev muaj zog, thiab txhim kho lub neej zoo rau cov neeg mob. Tsis tas li ntawd, Carbidopa pab txhawb rau lub qhov rais kho kom ntev dua thiab ruaj khov plasma ntau ntawm levodopa, uas yog tshwj xeeb tshaj yog muaj txiaj ntsig zoo hauv kev txo qis "tawm" lub sijhawm thiab kev hloov pauv ntawm lub cev muaj zog feem ntau ntsib hauv cov theem siab ntawm Parkinson tus kab mob. Nws kev koom ua ke rau hauv cov txheej txheem kho mob tau ua rau nws yog lub hauv paus hauv kev kho mob dopaminergic niaj hnub, txhawb nqa ob qho tib si luv luv - cov tsos mob nyem thiab ntev - cov tswv yim tswj xyuas lub sijhawm.
Xaus
Carbidopa Monohydrate yog ib qho tshuaj tseem ceeb hauv kev kho mob Parkinson tus kab mob, txhim kho kev ua tau zoo thiab kev nyab xeeb ntawm kev kho levodopa. Nws lub luag haujlwm hauv kev txo cov kev mob tshwm sim hauv peripheral thiab txhim kho qhov muaj nyob hauv nruab nrab ntawm dopamine ua rau nws yog ib qho tseem ceeb hauv kev kho mob ua ke, ua rau muaj txiaj ntsig zoo rau cov neeg mob kev nplij siab thiab kev ywj pheej ua haujlwm. Tshaj li kev siv tshuaj kho mob, nws ua haujlwm ua lub luag haujlwm tseem ceeb hauv kev tshawb fawb rau kev txhim kho kev xa tshuaj thiab kev tsim qauv. Zuag qhia tag nrho, Carbidopa Monohydrate piv txwv li cas lub hom phiaj enzyme inhibition tuaj yeem txhim kho cov txiaj ntsig kev kho mob, ua kom muaj txiaj ntsig zoo thiab ua kom ntev ntev hauv kev tswj cov hlab ntsha.
Cim npe nrov: Tuam Tshoj carbidopa monohydrate cas 38821-49-7 manufacturers, lwm tus neeg, Hoobkas
