Hangzhou Leind Chem Co., Ltd. yog ib qho ntawm cov neeg tsim khoom lag luam thiab cov chaw muag khoom ntawm Val {} mmAe}} mmAe}? Txais tos rau kev lag luam wholesale kev cai ua cov tshuaj lom neeg cov khoom lag luam ntawm cov nqi sib tw los ntawm peb lub hoobkas. Rau cov khoom lag luam pheej yig tshaj, tiv tauj peb tam sim no.
Cov lus qhia
| Zog: | Dawb rau tawm - dawb tawv |
| Daim qhia npe: | HPLC: Lub sijhawm khaws cia ntawm cov ncov siab loj tshaj plaws |
| Purity (los ntawm HPLC): | 98% min |
| Tag nrho cov impurity: | 2% Max |
Cov Ntawv Thov
Val - Cit -} pa {{mmae} mmae siv nyob rau hauv lubKev loj hlob thiab kev tsim cov tshuaj tiv thaiv - kev siv tshuaj conjugates, chav kawm ntawm biopharraceuticals uas ua ke tshwj xeeb ntawm monoclonhal tshuaj tiv thaiv nrog lub siab muaj zog ntawm cytotoxic tshuaj. TusVal - citDipepride Linker yog cathepsin b, ib qho enzyme overexpressed nyob rau hauv cov qog mis, kom pom tau tias MMOE them nyiaj sab hauv malignagant cov ntaub so ntswg. TusIbLub dav hlau txhawb nqa tus kheej -}}}}}}}}}}}}}}}} Cov kab mob enzymatic me me, tso dawb MMAE nyob rau hauv nws daim foos. MMA de ua raws li aMicroTuble Inhibitor, Tiv thaiv kev tiv thaiv ntawm tes thiab inducing apoptosis hauv cov qog nqaij hlav cancer. Qhov no conjugate moj khaum tau thov hauv ob peb fda {{1} Yuav ua tus qauv ADCS thiab txuas ntxiv ua kev tsim qauv tshiab hauv cov khoom siv hluav taws xob tshiab.
Cov txiaj ntsig
Cov txiaj ntsig ntawm Val - cit - pa {} mmake kav los ntawm nwsPrecision, potency, thiab modularityCov. Lub enzymatically coopable linker muab tshuaj tawm tshuaj tso tawm, yog li txo tawm tawm- hom phiaj cytooxicity thiab txhim kho lub hom phiaj kev ntsuas ntawm ADCS. Qhov kev ruaj ntseg ntawm cov ntawv txuas nyob hauv qab physiological siv kom muaj kev tso tawm tshuaj ua ntej, thaum lub sij hawm muaj kev pab ntau yam nyob hauv cov qog nqaij hlwb. MMAHE nws tus kheej yog qhov muaj zog cytotoxin, nquag ntawm sub {4 4}} cov qog nqaij hlav tseem ceeb, uas tsuas yog ib qho tshuaj sib txuas me me Tsis tas li ntawd, cov qauv qauv ntawm Val - mmooke tso cai rau cov khoom sib txawv thiab cov phiaj xwm kab mob qog noj ntshav, muab cov kab mob qog noj ntshav, muab tau yooj yim hauv ADC tsim.
Tag
Hauv cov ntsiab lus, Val - cit- mmake} pab- mmake} mmaking kev xa khoom thiab cov neeg sawv cev cytotoxic. Nws cov ntse ua ke ntawm kev ruaj khov, xaiv, thiab bioactivity ua rau nws siv tshuaj tiv thaiv {}} cov tshuaj tiv thaiv kev ua kom zoo. Los ntawm nws txoj kev koom ua ke rau hauv ob peb txoj kev ua tiav anticancer, val {}} mmook in tsom sij rau kev kho mob cancer.
Cim npe nrov: Val - cit- mmao}}}}}}} {}}}}}}} {}}}}}}}}
