Cov lus qhia
|
Zog: |
Dawb khoom |
| Purity (HPLC, 210NM): | 95% min |
| Kev Purity Ovority: | E 1 100% |
| Kev sib hloov tshwj xeeb [] 20D: | -28.9 Qib (DMF) |
| Mass Spectrum: | Raws li cov qauv |
| NMR Spectrum: | Raws li cov qauv |
Cov Ntawv Thov
1. Khoom-theem peptide synthesis (SPPS)
Siv raws li kev tiv thaiv amino acid tsev nyob rau hauv cov synthesis ntawm hloov peptides thiab peptidomimetics.
FMOC pab pawg ua rau cov pab pawg tau txais kev siv Peptides siv cov qauv fmoc-spps raws txoj cai.
Tus N-methyltrityl (mmt) pawg ntawm Lysine Sab Txoj Hlua pub Orte-amine thaum lub sijhawm lossis tom qab peptide sib dhos.
2. Qhov chaw kawm tshwj xeeb ntawm peptides
Pab txhawb kev xaiv sab-saw tsis txaus ntseeg rau:
Txuas cov ntawv cim fluorescent
Conjugation ntawm cov tshuaj (tshuaj-peptide conjugates)
Cov lus qhia ntawm kev hloov kho tshiab (piv txwv li, glycosylation mimics)
Ua rau cov kws kos duab nyuaj thiab ntau ntau peptides.
3. Peptidomimetic thiab Tshuaj Kho Mob
Muaj txiaj ntsig zoo nyob rau hauv cov synthesis ntawm hloov kho lysine-muaj peptides uas yog qhov tseem ceeb hauv kev kawm:
Epigenetic cim (piv txwv li, methylation ntawm Lysine seem)
Protein-protein kev sib cuam tshuam
Enzyme substrate tshwj xeeb
Lub n-methyltrityl kev tiv thaiv tiv thaiv undesired sab kev tawm tsam, txhim kho cov khoom siv hluavtaws thiab kev coj dawb huv.
4. Nchuav Peptide Library tiam
Siv Hauv Combinatorial Peptide Peptide cov tsev qiv ntawv rau qib-kev tawm tsam mus kuaj.
Enables kev sib txuam ntawm kev tiv thaiv kev tiv thaiv lysine seem rau cov kev xaiv qis lossis sau npe.
Cov txiaj ntsig
1. Orthous tiv thaiv pab pawg
FMOC thiab MMT pawg yog orthogonal, lub ntsiab lus:
FMOC tuaj yeem raug tshem tawm nyob rau hauv cov neeg mob me (piperidine).
MMT tuaj yeem raug tshem tawm xaiv nyob rau hauv cov acidic me ntsis yam tsis muaj kev cuam tshuam fmoc lossis peptide caj qaum.
Qhov no tso cai rau stepwise xaiv thiab kev ua haujlwm.
2. Txhim Kho Hluav Taws Xob Hluav Taws Xob
Lub MMT pab pawg lub Lability Pub tswj hwm sab-saw hloov pauv yam tsis muaj kev hloov pauv tsis txaus ntseeg.
Tau txais kev coj dawb huv thiab tawm los ntawm kev txo cov kev sib raug zoo thaum lub sijhawm SCPS.
3. Kev sib xyaw nrog cov qauv spps
Siab tau sib xws nrog automated peptide synthesizers thiab siv cov kev cai siv dav.
Tso cai rau cov synthesis ntawm ua rau pawg ua haujlwm nrog ntau pawg ua haujlwm thiab cov kev hloov kho tom qab.
4. Cov pab txhawb cov engineering inechering
Ua rau kev tsim bioconjugates, cov khoom siv cov tshuaj, thiab molecular pretes.
Pab tau nyob rau hauv kev tsim cov hom phiaj kho kho thiab kuaj mob.
Tag
FMOC-N-Methyltrityl-L-Lysine (CAS-l-l-l-l-l-l-l-l-l-l-l-l-l-l-l-l-l-l-l-l-l-l-l-l-l-ag2-6) yog kev tiv thaiv tshwj xeeb tsim rau kev siab heev-theem peptide synthesis. Kev tiv thaiv kev sib xyaw FMOC rau ntawm -Aamino pab pawg thiab n-methyltrityl (Side Side pinm (menino Side kev tiv thaiv, ua haujlwm ntawm Lysine sabins. Qhov no ua rau nws tsis tseem ceeb rau synthesizing hloov peptides, peptidomimetics, thiab cov kuab tshuaj bihoconumates, thiab cov tshuaj lom neeg biology, thiab kev tshawb nrhiav roj ntsha, thiab cov tshuaj tshawb nrhiav roj ntsha.
Cim npe nrov: FMOC-N-Methyltrityl-L-Lysine are Cas 167393-62-62-62-62-6
