18F-L-Dopa Precursor 丨 CAS 2377146-66-0

Lub 18F-L-Dopa precursor feem ntau yog siv rau hauv xov tooj cua ntawm18F-L-Dopa, siv dav siv PET (positron emission tomography) radiotracer rau neuroimaging. Nws ua kom muaj kev sib koom ua ke ntawm fluorine-18 mus rau hauv lub molecular molecular molecular molecular molecular, txhawb automated los yog semi-automated radiochemical ntau lawm. Cov neeg ua ntej no niaj hnub ua haujlwm nyob rau hauv kev npaj kho mob- thiab tshawb fawb-qib 18F-L-Dopa siv los ntsuas cov kab mob dopaminergic, suav nrog kev ntsuam xyuas cov kab mob Parkinsonian, kev txav chaw, thiab cov kab mob neurodegenerative. Nws kuj tseem siv rau hauv oncology imaging workflows, tshwj xeeb tshaj yog rau kev kuaj mob neuroendocrine hlav thiab qee cov qog hlwb uas qhia tias muaj zog amino-acid decarboxylase. Lub precursor cov qauv tshuaj tso cai rau kev xaiv cov ntawv sau npe raws li kev tswj xyuas, ua rau nws tsim nyog rau kev tsim kho tshuaj radiopharmaceutical, kev ua kom zoo dua qub, thiab kev tsim khoom hauv cyclotron / PET radiochemistry chaw.

Qhov precursor no muaj cov txiaj ntsig tseem ceeb vim nws qhov kev ua haujlwm siab rau nucleophilic lossis electrophilic 18F kev koom ua ke, nyob ntawm cov txheej txheem sau npe tshwj xeeb. Nws cov qauv tsim ua kom muaj cov khoom siv hluav taws xob zoo, txo lub sijhawm sib xyaw, thiab txhim kho kev ntseeg siab hauv cov tshuab hluav taws xob siv hluav taws xob ntau lawm. Lub precursor feem ntau ruaj khov txaus rau kev khaws cia thiab kev thauj mus los ntawm cov chaw siv hluav taws xob hluav taws xob, txhawb kev ua haujlwm zoo ib yam thaum lub sijhawm radiolabeling. Nws ua kom zoo tiv thaiv pab pawg thiab kev ua haujlwm zoo txo ​​qis qhov tsis xav tau sab nraud, ua rau muaj hluav taws xob zoo purity ntawm qhov kawg 18F-L-Dopa khoom. Cov txiaj ntsig zoo no pab txhawb rau kev tsim khoom PET tracer, zoo dua duab zoo, thiab txhim kho kev ua haujlwm zoo hauv chaw kho mob thiab tshawb fawb radiopharmacies.