Hangzhou Lep Chem Co., Ltd. yog ib qho ntawm cov neeg lag luam thiab cov neeg muag khoom ntawm 7-cycloro-1-cycloquinyc-1-cyclboxoline-3-carboxylic acid are 86393-33-1 hauv Suav teb. Txais tos rau kev lag luam wholesale kev cai ua cov tshuaj lom neeg cov khoom lag luam ntawm cov nqi sib tw los ntawm peb lub hoobkas. Rau cov khoom lag luam pheej yig tshaj, tiv tauj peb tam sim no.
Cov lus qhia
| Tus cim | Tawm - dawb lossis tsaus muag daj hmoov |
| Kev coj dawb huv | 99.0% min |
| Kev txheeb xyuas (HPLC) | Tau raws li qhov yuav tsum tau ua |
| Cov ntsiab lus (ntawm lub anhydrous hauv paus) | 98.5% min |
| Poob rau ziab | 0.50% max |
| Tag nrho cov neeg tawg | 1.0% max |
| Max. Ib Leeg Cav | 0.80% max |
Cov Ntawv Thov
7 {-}} 10}}}}}} Cyclopropyl-6 -4-} Cyclopropyl-4-} Byclopropyl-4-} Nws cov qauv Quinolone tseem ceeb, ua ke nrog Halogen thiab Cyclopropy hloov chaw ua haujlwm, muab lub hauv paus rau kev tsim cov tshuaj tua kab mob DNA hom Gyrase thiab Topoisomerase IV. Nws tau thov hauv kev tshawb fawb me me los tsim cov kev ua haujlwm tshiab nrog cov kab mob ua kom zoo nkauj tawm tsam gram-zoo thiab gram-tsis zoo cov kab mob. Ib qho ntxiv, nws ua haujlwm rau cov qauv-kev sib raug zoo (SAR) cov khoom lag luam los ua kom cov kws tshawb fawb pom zoo, thiab kev nyab xeeb tshaj lij hauv kev tsim cov tshuaj tua kab mob.
Cov txiaj ntsig
Qhov compound muaj cov txiaj ntsig tseem ceeb vim nws reinolone scaffold thiab cov tswv yim muab cov chaw hloov chaw. Lub 6 {{{{4} fluoro thiab 7 {{{}} Cycloro, thaum lub 1 {- spectrum ua tau zoo. Nws qhov ruaj khov thiab txhais tau tias ua tau zoo sib xws ua rau kev hloov kho cov tshuaj lom neeg uas muaj kuab lom, yooj yim synthesis ntawm cov fluoroquinolone derivatives. Tsis tas li ntawd, nws tso cai rau kev hloov kho meej ntawm ntau txoj haujlwm ntawm lub nplhaib quinolone nrog txhim kho solubility, bioavailability, thiab txo cov peev txheej tsis kam. Zuag qhia tag nrho, nws ua kom nrawm dua cov kev tsim cov tshuaj ntsuam muaj nqis muaj nuj nqis.
Tag
7 {-} fluoro-1-fluoro-4,4-oxoquyro-4-oxoquin-4-carboxylic acid yog qhov tseem ceeb hauv kev tshawb tshuaj. Nws Quinolone tus tub ntxhais, ua ke nrog Halogen thiab Cyclopropyl hloov chaw, muab ib qho kev sib zog rau cov tshuaj tua kab mob fluoroquinolone thiab tshawb xyuas cov derivatives tshiab. Los ntawm kev txhim kho cov khoom siv thiab kev ua kom zoo dua qub, nws ua lub luag haujlwm tseem ceeb hauv kev txhim kho cov neeg sawv cev tom ntej no nrog kev nyab xeeb ua tau zoo thiab kev nyab xeeb profiles.
Cim npe nrov: 7-chloro-1-cycloproyl-6,4-oloquyro-4-coloquin-4-cycloro-4-oloquydro-4-oloquinoline-3-carboxylic acid 丨 cas 86393-33-1 Cov Chaw Tsim Tshuaj, Cov Chaw Muag Khoom, Hoobkas
