Cov lus qhia tshwj xeeb ntawm 4,5,7-tetrahydro-5-Methyl-Thiazolo5,4-cpyridine-2-carboxylic acid hydrochloride 丨 CAST 720720-96-7
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Zog: |
Dawb rau cov hmoov daj |
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Assisy (ntawm cov dej qhuav): |
98.0–102% |
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Daim qhia npe: |
Nyob rau hauv cov chromatograms ntawm cov ntaub ntawv tiv thaiv yeeb yaj kiab uas muaj feem xyuam rau lub sijhawm tseem ceeb ntawm cov tshuaj sim thiab cov khoom siv yuav tsum sib xws. |
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Lwm yam tshuaj (% thaj chaw ib txwm los ntawm HPLC): |
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4,5,6,7-tetrahydro-5-Methylthiazolo [5,4-c] pyridine: |
2.0% Max |
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Ib qho impurity: |
0.3% max |
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Tag nrho cov impurities: |
2.5% Max |
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Purity: |
97.5% min |
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Dej: |
1.0% max |
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Sulfated tshauv: |
0.5% max |
Cov ntawv thov ntawm 4,5,7-tetrahydro-5-Methyl-Thiazolo5,4-cpyridine-2-carboxylic acid hydrochloride 丨 CAST 720720-96-7
1. Tshuaj Nruab Nrab
Feem ntau siv raws li aSynthetic Nruab NrablossisLub Tsev ThaivhauvKev Tshawb Xyuas Tshuaj thiab Tshuaj Kho Mob.
Thiazolopyridine core yog aTus qauv tsim nyogHauv kev siv tshuaj chemistry, pab txhawb rau kev ua pob xws li:
Tus kab mob antimicrobial
Tshuaj ntxuav
Los tiv thaiv
Cns-nquag sawv cev
2. Heterocyclic Compound
Kawm hauv kev txhim kho ntawmTshiab Heterocyclic Scaffolds, tshwj xeeb hauvKev tsim qauv ntawm enzyme inhibitors, ion channel modulators, lossis receptor ligands.
Nws lub tsheb pob tw tsheb sib txhawb txhawb nqaPhiaj-tshwj xeeb khi kev sib txawvnyob rau hauv kev siv hluav taws xob.
3. Kev Tshawb Fawb thiab Kev Tshawb Fawb
Ua hauj lwm ua tus qauv siv lossis prefursor hauvTus qauv-kev ua si sib raug zoo (SAR)Kev tshawb fawb thiab kev sib txuas ua ke.
Lub Hydrochloride Daim Ntawv Txhim Khosolubility thiab ruaj khov, Kho kom yooj yim tuav hauv aqueous lossis acidic media.
Cov txiaj ntsig
1. Biologically cuam tshuam scaffold
TusThiazolo [5,4-c] Pyridine Coreyog analog rau ntuj bioactive molecules thiab feem ntau siv hauv cov tshuaj txhuas ua kom zoo dua.
Muaj peev xwm rausiab receptor binding tshwj xeebthiabmembrane permeability.
2. Khoom cua verstility
Cov carboxylic acid pab pawg pub rau:
Amide lossis Ester Coupling
Ntsev Kev Tsim
Protrrug Kev Loj Hlob
Tuaj yeem koom nrogPeptide Mintetics, Macrocycles, lossisCov tshuaj conjugates.
3. Txhim Kho Cov Qauv Tsim Qauv
Raws li ahydrochloride ntsev, nws yog ruaj khov thiabyooj yim rau kev ntxuav thiab tsimTshaj li nws cov ntaub ntawv qub, uas yog pab tau nyob rau hauv cov tshuaj R & D thiab thaum ntxov-theem kev sim ua.
Tag
4,5,6,7-tetrahydro-5-ciazolo5,4-cpyridine-2-carboxylic acid hydrochloride 丨 CAST 720720-96-7 yog aTshwj xeeb heterocyclic compounddav siv nyob rau hauvKev Siv Tshuaj Kho Mob TshuajthiabTshuaj Kho Mob TshuajCov. Nws sib xyaw ntawm cov figid fused system nrog cov kev ua haujlwm acid pab pawg thiab txhim kho solubility ua cov cuab yeej hydrochloride ua rau nws muaj txiaj ntsig zoo hauv cov khoom siv hauv synthesis ntawmHom Phiaj Bioactive Molecules.
Cim npe nrov: 4,5,6,7-tetrahydro-5-cpyrorine-2-carboxylic acid hydrothylorine-2-carboxylic acid hydrochlicide 丨 CAS 720720-96-96-96-9 VACHATORERS, cov chaw muag khoom, Hoobkas
