(3S,4R)-tert-Butyl 3-amino-4-fluoropiperidine-1-carboxylate丨CAS 1290191-73-9

Cov compound no yog feem ntau siv nyob rau hauvKws Tshuaj thiab Tshuaj Txom NyemRaws li lub tsev thaiv rau cov synthesis ntawm chiral piperidine -} raws tshuaj. Fluorine atom Exchances Letholic Stability, Liplophilicity, thiab khi kev tiv thaiv AMino-}} theem synthesis. Nws tau ua haujlwm hauvXyuas Yeeb TshuajRau kev txhim kho ntawm central ntawm cov hlab ntsha cov neeg sawv cev, enzyme inhibitors, thiab cov receptor modulators. HauvOrganic Synthesis, nws ua haujlwm ua ib theem nrab rau tsim cov kev ua haujlwm siab, peptide mimetics, lossis lwm cov nitrogen {}}}}}}}}} nws muaj cov scaffolds bioactive. Nws cov kev ua kom muaj txiaj ntsig zoo tshwj xeeb tshaj yog qhov tshwj xeeb rau kev tsim cov enantiomerically txhais tau cov tebchaw, uas yog qhov tseem ceeb rau kev ua tiav kev ua tshuaj lom.

Cov txiaj ntsig ntawm (3s, 4r)- tert {}} butoropiperidium-1-carboxylate suav nrog nwsTxhais tau hais tias SereOchemistry, cov tshuaj siv tshuaj lom neeg, thiab sib xyaw nrog cov kev hloov pauv hluavtawsCov. Lub tert - butyl carbamate tiv thaiv cov nitrogen atom thaum cov kev coj ua, cia cov roj carbon amino lossis cov tshuaj fluorinated. Nws cov tshuaj fluorine hloov tau txhim kho kom muaj kev ruaj khov, kev ua haujlwm roj ntsha, thiab membrane permeratility ntawm derivatives. Cov compound yog soluble nyob rau hauv ib txwm organic cov kuab tshuaj thiab ruaj khov nyob rau hauv cov kab mob kuaj mob, ua kom nws yooj yim rau hauv multi- qib hluavtaws ua ntu zus. Nws Chiral Kev Ncaj Ncees uas ntseeg tau tias cov khoom lag luam hauv dej los khaws cov enantiomourcer purity, uas yog qhov tseem ceeb rau cov tshuaj ntsuab.