{{0 {0}} Aminopyridine -4- methanol 丨 CAS 105250-17-7

{{0 {0}} Aminopyridine {}}}}}}}}}}}}} Yog cov feem ntau siv los ua lub tsev thaiv hauv cov articy synthesis. Nws cov qauv muaj ib lub nplhaib pyridine nrog cov pab pawg amino (-NH2) ntawm {} txoj haujlwm, thiab nws feem ntau koom nrog hauv kev siv tshuaj thiab kev siv roj ntsha.
Txuj ca
{{0 {0}} Aminopyridine {}}}}}}}}}} Txheem cov amino thiab hydroxymethyl pab pawg. Ib txoj kev ib txwm koom nrog hydroxymethylation ntawm {3}}} inepyridine lossis cov sib xyaw ua ke los txuas cov pab pawg hydroxethyl ntawm txoj haujlwm tsim nyog.

1.Qhia thiab tshuaj chemistry:
Odrug Kev Loj Hlob: {2-} {}}}}}}}}}}}}}}}}}}}}}} Lub pyridine thiab pawg amino pawg feem ntau koom nrog cov molecules uas cuam tshuam nrog enzymes, receptors, lossis lwm yam hom phiaj.
Okinase inhibitors: nws yuav siv nyob rau hauv cov synthesis ntawm Kinease inibitors, uas yog qhov muaj txiaj ntsig zoo hauv kev kho mob qog nqaij hlav, thiab lwm yam mob. Lub aminopyridine scaffold paub txog nws lub peev xwm los khi rau ATP-khi qhov chaw ntawm qee qhov kev cog lus rau kev tsim cov kev xaiv tsis pub lwm tus neeg.
OTticancer Kev Tshawb Fawb: Hauv kev tshawb fawb, nws tau tshawb nrhiav ua ib feem ntawm cov sib txuas ua ke tsim los ua cov phiaj xwm tshwj xeeb hauv cov qog nqaij hlav cancer. Cov pab pawg hydroxsyl tuaj yeem ua lub luag haujlwm hauv kev txhim kho lub solubility thiab ruaj khov ntawm cov tebchaw no.
2.organic synthesis:
Ob qho kev sib txuas ua ke: Cov compound yog siv los ua hluav taws xob rau cov synthesis ntawm ntau nyuaj organic sib sau, tshwj xeeb tshaj yog nyob rau hauv teb ntawm Heterocyclic Chemistry. Nws cov pab pawg ua haujlwm-amino thiab hydroxymethyl-yog cov muaj nqis rau kev kho cov khoom hluav taws xob ntawm lwm cov molecules.
Opyridine derivatives: Nws tuaj yeem ua ib qho nrab hauv synthesis ntawm pyridine derivatives, uas yog qhov tseem ceeb hauv kev tsim cov dyes, tshuaj tua kab, thiab kws tshuaj. Nws lub peev xwm los ua rau ntau yam kev hloov pauv tau ua rau nws muaj ntau yam nruab nrab hauv cov khoom siv tshuaj.
3.Calysis:
ETHE hydroxymethyl pab rau lub nplhaib pyridine tuaj yeem koom nrog qee yam kev sib cav sib ceg, tshwj xeeb yog cov kev cuam tshuam nrog nucleophilic nres lossis oxidation txheej txheem. Raws li cov lus tshaj tawm, qhov sib xyaw ua ke tuaj yeem koom nrog kev sib koom tes ua haujlwm, uas cov nitrogen nyob rau hauv lub pyridine ntiv nplhaib ua cov khoom pub rau cov hlau, ua rau nws muaj txiaj ntsig hauv kev hloov tsheb hlau catalysis.
Oits qauv tseem yuav tso cai rau nws los cuam tshuam nrog kev hloov cov hlau catalysts hauv kev sib pauv sib txuas lossis lwm yam kev hloov pauv hluavtaws.
4.Biological Trace:
OzyKyme Inhibition: Vim muaj cov amino pab pawg thiab cov pyridine, cov compound no yuav pab tau nyob rau hauv kev kawm enzyme inhibition. Nws yuav cuam tshuam nrog cov enzymes tshwj xeeb, xws li monesamine oxidase lossis cov kev tiv thaiv, ua rau nws muaj txiaj ntsig zoo rau kev nkag siab enzyme muaj nuj nqi lossis enzyme inhibition.
Kev tshawb fawb ib qho: Pyridine derivatives zoo li 2-}}}}}}}}}}}} urochemical pathwact nrog neurotransmitter tshuab. Cov pab pawg amine tuaj yeem cuam tshuam nrog cov receptors lossis enzymes koom nrog cov kev cai ntawm neurotransmitter.
5.Yagricure thiab Kab Tsuag Tswj:
Ope Pyridine qauv feem ntau siv hauv kev tsim cov tshuaj tua kab thiab tshuaj tua kab. Thaum 2- o} aminopyridine {}}}}}}}}}} kev ua haujlwm lossis cov sib txuas lus muaj feem yuav muaj feem rau cov laj thawj no.
Oherbicide lossis cov tshuaj tua kab tsuag yuav tau txais txiaj ntsig los ntawm kev sib xyaw muaj peev xwm cuam tshuam nrog cov txheej txheem metabolic hauv cov kab mob sib txawv, ua yeeb yam raws li tus neeg sawv cev raug.

2- Aminopyridine -4-}}}}}}}}}} Kev Tshawb Fawb, Kev Tshawb Nrhiav Kev Lag Luam Hluav Taws Xob Nws cov amine thiab hydroxymethyl pab pawg ua rau nws muaj txiaj ntsig zoo rau synthiving rau synthiving cov tebchaw, tshwj xeeb yog cov koom nrog inhibition, antimicrobial, thiab anticancer kev tshawb fawb. Nws siv hauv catalysis thiab enzyme kev tshawb fawb ntxiv dav nws cov ntawv thov yuav muaj nyob rau hauv ob qho kev tshuaj lom hluav taws xob thiab tshuaj pom kev tshuaj. Thaum nws suav hais tias nws muaj kev nyab xeeb rau kev sim hauv kev kuaj teeb meem, tsim nyog kev ceev faj yuav tsum tau ua kom tsis txhob muaj tawv nqaij, qhov muag, lossis ua pa tawm lossis ua pa tawm.