2-amino-5-chloro-2,6-diflluorobenobenobenobenobenzophenone 丨 :83-0

2 {- amino-}}}}}}}}}}} pertely siv raws li kev sib cais hauv cov tshuaj nruab nrab thiab zoo tshuaj lom neeg. Nws pabcuam ua lub tsev thaiv kev npaj ntawm kev sib txuas ntawm Heterocclic Teb, suav nrog Artiviral, tshuaj tua kab mob, thiab anticancer sawv cev. Nws multifunctional qauv, muaj amino, chloro, xws li kev xaiv nucleophilic hloov chaw, hws, thiab sib txuas ua ke, thiab sib txuas ua ke. Qhov sib txuas kuj tseem ua haujlwm hauv synthesis ntawm dyes, agonemicals, thiab lwm yam kev ua yeeb yam uas halogenated thiab amino-hloov cov menomatic system. Hauv kev tshawb fawb, nws yog siv rau kev tsim qauv thiab kev nthuav dav ntawm cov khoom siv hluav taws xob hauv hluav taws xob thiab cov khoom siv uas txhawb nqa cov khoom lag luam thiab cov qauv tshuaj.

Cov compound muaj ob peb qhov zoo vim nws cov qauv ua haujlwm uas muaj ntxhiab. Cov amino pab pawg muab lub xaib rau kev ua haujlwm ntxiv, thaum difluoro tsis hloov, thiab cov khoom hluav taws xob ntawm cov khoom siv hauv qab. Nws lub siab {- Txhais tus qauv tso cai rau cov kev sib haum xeeb thiab rov ua dua tshiab hauv ntau {}} kev tshaj tawm cov khoom siv, txhim kho cov txiaj ntsig thiab kev ua tau zoo. Lub xub ntiag ntawm fluorine atoms tuaj yeem txhim kho Lipophilicity, thiab receptor- binding cov yam ntxwv, uas yog tshwj xeeb tshaj nyob rau hauv cov tshuaj muaj kev txhim kho. Tsis tas li ntawd, cov compound yog ruaj khov nyob rau hauv cov kev xaiv kev cia, tau tshaj tawm cov kuab tshuaj thiab kev lag luam hauv ob qho kev lag luam hauv ob qho kev sib tw.