1-fluoro-cyclopropanlicboxylic acid 丨 CAS 137081-41-5

1. Tshuaj Nruab Nrab Nruab Nrab

Siv los ua lub tsev tseem ceeb hauv cov hluavtaws ntawm ntau yam khoom sib xyaw.

Qhov tseem ceeb tshwj xeeb hauv kev tsim ntawm cov molecules uas fluorine txhim kho kev ruaj khov thiab bioavailability.

Yuav siv nyob rau hauv kev npaj cov tshuaj fluorinated cov tshuaj fluorinated, tshwj xeeb hauv antiviral, anticancer, thiab CNS-act-accounds.

2. Agochnical synthesis

Ua haujlwm ua tus thawj coj los yog nruab nrab hauv kev txhim kho cov tshuaj tua kab mob tshuaj ntsuab, tshuaj tua kab, lossis cov fungicate uas muaj fluoropnane motifs.

Fluorination tuaj yeem txhim kho Liplophilicity, hom phiaj xaiv, thiab tsis kam mus rau kev ua kom muaj kev cuam tshuam hauv cov nroj thaiv kev tiv thaiv.

3. Khoom siv hluavtaws organic

Ua haujlwm nyob rau hauv lub nplhaib-qhib kev tshwm sim, Esterification, thiab Amide tsim rau tsev ua cov molecules.

Nws lub nplhaib sib dhos thiab cov tshuaj fluorine hloov chaw muab kev sib zog ua kom muaj kev nce qib hauv Ingisfluorine Chemistry.

4. Kev loj hlob ntawm cov neeg tshwj xeeb fluorochemicals

Yuav siv tau rau hauv synthesis ntawm fluorinated monomers thiab cov ntaub ntawv ua haujlwm rau kev siv hauv cov ntaub ntawv siab heev thiab cov ntaub ntawv hluav taws xob.

✅ Fluorine Ua Haujlwm
Cov tshuaj fluorine atom nce ntxiv:

Lipophilicity

Tshuaj lom neeg thiab kev ruaj khov ruaj khov

Binding affinity hauv cov hom phiaj biological

✅ Cyclopropane Ntiv nplhaib lim
Lub voj voos ci ntsa iab:

Qhia txog kev ua txhaum cai

Txhim kho cov neeg tau txais kev xaiv npe thiab cov phiaj xwm phiaj xwm

Pab txhawb kev ua cov kev tswj hwm hauv cov nyom molecule synthesis

✅ Versetity ntau yam
Cov carboxylic acid pab pawg ua:

Ester thiab Amide Kev Ua Haujlwm

Sib sau nrog peptide Coupling kev tawm tsam

Nqi hluav taws xob hauv cov tshuaj lom-raws li cov tshuaj tsim (FBDD)

✅ Compact qauv
Qhov zoo tagnrho rau cov qiv nyiaj fragment thiab taug txhuas odtimization uas me me, zoo siab molecules yog xav tau.