Hangzhou Leap Chem Co., Ltd. yog ib qho ntawm cov kws tshaj lij thiab cov neeg muag khoom ntawm icatibant acetate 丨cas 138614-30-9 hauv Suav teb. Txais tos rau kev lag luam wholesale kev cai ua cov khoom lag luam ntawm tus nqi sib tw los ntawm peb lub hoobkas. Rau cov khoom pheej yig dua, tiv tauj peb tam sim no.
Specifications
| Qhov tshwm sim | hmoov dawb |
| Purity (los ntawm HPLC) | 98% min |
| Ib qho Impurity (HPLC) | 2% max |
| Cov ntsiab lus Acetate (HPLC) | 12% max |
| Cov ntsiab lus Peptide (N%) | 80% min |
| Cov ntsiab lus dej (KF) | 10% max |
| MS (ESI) | ua raws |
Daim ntawv thov
Icatibant acetate yog ib qho hluavtaws peptide siv feem ntau hauv kev tshawb fawb tshuaj thiab biomedical raws li kev xaiv bradykinin B2 receptor antagonist. Clinically, nws yog thov rau kev kho mob ntawm hereditary angioedema (HAE) kom sai sai txo qhov mob ntawm o los ntawm kev thaiv bradykinin - nruab nrab vascular permeability. Hauv kev tshawb fawb chaw, nws yog siv los kawm txog bradykinin signaling pathway, vascular biology, o, thiab lub luag hauj lwm ntawm B2 receptors nyob rau hauv lub plawv thiab inflammatory mob. Lub compound tseem yog siv los ua ib qho kev siv hauv kev tshawb fawb txog kev kho mob thiab tshuaj kho mob los ntsuas qhov ua tau zoo, pharmacokinetics, thiab receptor khi ntawm peptide tshiab lossis me me -molecule B2 receptor antagonists. Nws cov dej-soluble acetate daim ntawv tso cai rau kev npaj yooj yim hauv kev sim thiab cov qauv tshuaj kho mob.
Cov txiaj ntsig
Icatibant acetate muaj ntau qhov zoo uas ua rau nws muaj txiaj ntsig hauv kev kho mob thiab kev tshawb fawb. Nws qhov tshwj xeeb tshwj xeeb rau bradykinin B2 receptors ua kom lub hom phiaj ua haujlwm, txo qis - cov teebmeem thiab kev txhim kho kev nyab xeeb hauv kev siv tshuaj kho mob. Lub peptide qhov pib sai sai ntawm kev ua haujlwm muab kev pab sai sai hauv HAE kev tawm tsam, ua kom pom kev zoo receptor blockade hauv vivo. Nws ruaj khov raws li acetate ntsev txhim kho kev solubility thiab ua kom yooj yim tsim rau kev txhaj tshuaj lossis kev kuaj sim. Hauv kev tshawb fawb, Icatibant acetate yog ib qho cuab yeej txhim khu kev qha los tshawb txog bradykinin-txoj kev cuam tshuam, kev sib cuam tshuam ntawm receptors, thiab cov txheej txheem inflammatory, txhawb kev tshawb nrhiav tshuaj thiab kev tshawb fawb siv tshuab. Nws qhov zoo-tus yam ntxwv ntawm tus kws kho mob profile tso cai rau cov txiaj ntsig zoo sib xws thiab rov tsim dua thoob plaws cov kev tshawb fawb.
Xaus
Icatibant acetate yog ib qho kev xaiv bradykinin B2 receptor antagonist nrog kev siv hauv kev kho mob ntawm cov kab mob angioedema thiab hauv kev tshawb fawb biomedical. Nws qhov tshwj xeeb receptor tshwj xeeb, kev ua haujlwm sai, thiab solubility ua rau nws yog tus neeg sawv cev kho mob zoo thiab muaj txiaj ntsig zoo rau kev kawm bradykinin- txoj hauv kev sib kho. Zuag qhia tag nrho, Icatibant acetate txhawb nqa ob qho tib si kev tswj hwm ntawm qhov mob o thiab kev tshawb fawb siv tshuab rau hauv cov txheej txheem vascular thiab inflammatory.
Cim npe nrov: Tuam Tshoj icatibant acetate cas 138614-30-9 manufacturers, lwm tus neeg, Hoobkas
