Cov lus qhia
| Teem nqi | USP43 |
| Kev tshwm sim | Dawb rau tsaus muag daj hmoov |
| Assay (ntawm anhydrous thiab btht - dawb hauv paus, muaj c53h83no14) | 98.0% ~ 102.0% |
| Kev sib hloov tshwj xeeb (ntawm anhydrous thiab btht - dawb dawb) | -141.0 Degree ~ -153.0 Degree |
| Daim qhia npe | |
| HPLC | Lub sijhawm khaws cia ntawm cov chromatogram tau txais los ntawm kev ntsuas daws yuav tsum sib haum rau cov uas tau los ntawm cov kev daws teeb meem, raws li tau txais hauv assay |
| Kuv | Spectrum ntawm cov qauv yuav tsum sib haum rau qhov ntawm cov qauv siv |
| Impurity b | 0.5% max. |
| Impurity c | 0.8% max. |
| Neeg los rhaub | 0.8% max. |
| Impurity kuv | 0.8% max. |
| Ib tug neeg unspecifypifecified impurity | 0.10% Max. |
| Tag nrho cov impurities | 2.5% Max. |
| Sirolimus | 0.15% Max. |
| Residual cov kuab tshuaj | |
| Methanol | 3000ppM Max. |
| Mthyl Dffect | 100PPM Max. |
| Ethanol | 5000ppMM Max. |
| IsoPropanol | 1000ppm max. |
| Dichhloromethane | 600PPM Max. |
| Ethyl Acetate | 1000ppm max. |
| 1,2-dimethoxyethane | 100PPM Max. |
| Triethylamine | 320PPM Max. |
| n - heptane | 1000ppm max. |
| Toluene | 890PPM Max. |
| Ethylene glycol | 620PPM Max. |
| Dej (Kf) | 1.5% Max. |
| Residue ntawm ignition | 0.1% Max. |
| Microbial txwv | |
| C | 1000 cfu / g max. |
| Tymc | 100 cfu / g max. |
| E. coli | Yuav tsum tsis tuaj |
Cov Ntaub Ntawv Thauj
|
Chaw ua uas tsis tau haus |
Kev qhia tshwj xeeb |
|
UN NUM |
3077 |
|
Hom |
9 |
|
Cov Pab Pawg |
I |
|
Hs code |
|
|
Ruaj khov & rov ua |
Cov khoom lag luam ruaj khov nyob rau hauv cov qauv ambient ambient. |
|
Chaw ntim khoom |
Khaws cov thawv ntim kom ruaj khov kaw hauv ib qho qhuav thiab zoo - ventilated qhov chaw. Pom zoo cia cov ntsuas kub -20 degree |
|
Mob kom tsis txhob |
|
|
Lub thawv |
Cov ntaub ntawv raug
|
Chaw ua uas tsis tau haus |
Kev qhia tshwj xeeb |
|
Lub peev xwm |
50kg / hli |
|
Hov ntau |
|
|
Lub teb chaws tseem ceeb |
|
|
Peev Xwm / Batch |
|
|
Paub lawm |
Ntau lawm txij xyoo 2015 |
|
Ntxiv rau |
Cov Ntawv Thov
Everolimus (CAS 159351 - 69-6) yog ib qho kev sib tw ntawm rapamycin thiab ua haujlwm ua cov hom phiaj ntawm cov tsiaj txhu cov phiaj xwm ntawm rapamycin (mtor). Nws yog dav siv nyob rau hauv lub chaw tshuaj ntsuam kws tshuaj raws li kev immunisuppressant los mus kho mob qog noj ntshav, thiab cov tshuaj tiv thaiv kab mob ntawm lub mis, thiab cov pab pawg ntawm lub cev nqaij daim tawv nqaij Tsis tas li ntawd, nws muaj cov ntawv thov hauv Cardiology los ntawm kev pab cuam-kev tu tshuaj-kev pab cuam los ntawm kev tiv thaiv cov leeg cell qhov kev cuam tshuam. Hauv kev tshawb fawb, Everolimus tau kawm kev kawm ntawm tes, cov metabolism, thiab cov phiajcim tseem ceeb thiab kev sim ua haujlwm.
Cov txiaj ntsig
Cov txiaj ntsig ntawm Apathabus tau khi ze rau nws lub luag haujlwm hauv kev txhaj tshuaj thiab oncology. Los ntawm xaiv tsis pub inhibiting mtor, nws tswj cov xovtooj ntawm tes, angiogenesis, thiab kev ciaj sia taus, muab cov phiaj xwm ua tau zoo tiv thaiv qog nqaij thaum muaj kev siv tshuaj lom rau cov kws kho mob ib txwm muaj. Nyob rau hauv kev hloov pauv, nws muaj ntev - lub sij hawm muaj kev pheej hmoo muaj kev pheej hmoo ntawm kev tsis lees paub, feem ntau ua ke nrog lwm yam immunosuppressants. Nws teeb tsa rau hauv cov hlab ntsha stents tau txo qis qis qhov tshwm sim ntawm kev so, txhim kho cov neeg mob cov txiaj ntsig. Tshaj li cov nyiaj kho mob, EverOlimus kuj tseem ceeb rau kev tshawb fawb, enabling cov ncauj lus kom ntxaws ntawm MTOR txoj kev, uas yog qhov tseem ceeb rau ntau yam kab mob. Nws cov versatility hla ntau thaj chaw kho mob uas tsis cuam tshuam nws cov kev cuam tshuam rau cov tshuaj niaj hnub.
Tag
Hauv cov ntsiab lus, Everolimus yog ib qho tseem ceeb ntawm kev sib txuas nrog cov ntawv thov hauv oncology, kev hloov pauv, plawv, thiab biomedical kev tshawb fawb. Nws cov txiaj ntsig suav nrog kev tsom xam cov neeg mob ntawm tes, txhim kho cov neeg mob ua kom muaj mob cancer thiab kev hloov pauv ntawm theem vascular. Raws li ob qho chaw kuaj mob thiab cov cuab yeej tshawb nrhiav, tus neeg xiam oob khab txuas ntxiv txhawm rau nkag siab txog cov tswv yim kho thiab sib cav sib ceg.
Cim npe nrov: Everolimaus 丨 CAS CAS 159351-69-69-6, Tuam Tshoj EverOlimus 丨 Cas 159351-69 manufacturers, lwm tus neeg, Hoobkas
