Hangzhou Leap Chem Co., Ltd. yog ib qho ntawm cov tuam txhab tshaj lij thiab cov chaw muag khoom ntawm doxorubicin hydrochloride丨cas 25316-40-9 hauv Suav teb. Txais tos rau kev lag luam wholesale kev cai ua cov khoom lag luam ntawm tus nqi sib tw los ntawm peb lub hoobkas. Rau cov khoom pheej yig dua, tiv tauj peb tam sim no.
Specifications
| Qib | USP38 |
| Qhov tshwm sim | Txiv kab ntxwv - liab crystalline hmoov |
| Assay (los ntawm HPLC) | 98.0% -102.0% ntawm anhydrous thiab hnyav dawb hauv paus |
| pH | 4.0-5.5 |
| Solubility | Soluble hauv dej, hauv isotonic sodium chloride tov thiab hauv methanol. Xyaum insoluble hauv chloroform, hauv ether thiab hauv lwm cov kuab tshuaj organic |
| Kev txheeb xyuas | Lub sijhawm khaws cia ntawm Doxorubicin ncov nyob rau hauv chromatogram ntawm Assay kev npaj sib raug rau qhov ntawd hauv cov qauv kev npaj raws li tau txais hauv Assay |
| Crystallinity | Ua tau raws li cov cai ntawm USP |
| Acetone thiab cawv | Tsis ntau tshaj 2.5% |
| Acetone | Tsis ntau tshaj 0.5% |
| Methanol | Tsis ntau tshaj 500ppm |
| Dichloromethane | Tsis ntau tshaj 500ppm |
| n-Propanol | Tsis ntau tshaj 5000ppm |
| 1,4-Dioxane hmoov | Tsis ntau tshaj 250ppm |
| Chloroform | Tsis ntau tshaj 60 ppm |
| Dej | Tsis ntau tshaj 4.0% |
| Doxorubicinone | Tsis ntau tshaj 0.5% |
| Daunorubicin | Tsis ntau tshaj 0.5% |
| Epirubicin HCl | Tsis ntau tshaj 0.5% |
| Lwm yam impurity | Tsis ntau tshaj 0.5% |
| Tag nrho impurities | Tsis ntau tshaj 2.0% |
| Cia | Nyob rau hauv ib lub thawv airtight, tiv thaiv los ntawm lub teeb, khaws cia hauv qhov chaw qhuav hauv qab 25 degree |
Daim ntawv thov
Doxorubicin hydrochloride yog dav siv nyob rau hauv oncology raws li ib tug anthracycline chemotherapeutic tus neeg saib xyuas rau kev kho ntau yam ntawm cov qog nqaij hlav. Nws muaj nyob rau hauv ntau txoj kev kho mob tsim rau cov qog nqaij hlav thiab hematological malignancies vim nws muaj peev xwm cuam tshuam nrog DNA replication thiab cell division. Nws yog siv rau hauv kev tswj cov qog nqaij hlav hauv lub mis, mob qog noj ntshav ntawm zes qe menyuam, mob qog noj ntshav, mob qog noj ntshav, mob ntsws cancer, cov nqaij mos sarcomas, thiab cov qog nqaij hlav hauv menyuam yaus, nrog rau lymphomas thiab leukemias. Hauv cov chaw tshawb fawb, cov tshuaj nquag siv los ua tus neeg sawv cev tiv thaiv kab mob los kawm txog cov txheej txheem ntawm cytotoxicity, apoptosis, tshuaj tiv thaiv, thiab qog biology. Nws kuj tseem siv tau rau hauv kev tshawb nrhiav uas muaj cov phiaj xwm xa tshuaj xws li liposomes, nanoparticles, thiab cov tshuaj tiv thaiv kab mob-cov tshuaj sib txuas, ua rau nws ua cov qauv sib xyaw hauv cov kev tshawb fawb txhawm rau txhim kho cov tshuaj chemotherapeutic xaiv thiab txo cov kab mob toxicity. Tsis tas li ntawd, doxorubicin hydrochloride yog siv nyob rau hauv lub chaw soj nstuam soj ntsuam oxidative kev nyuaj siab, DNA puas teb, thiab cell- voj voog txoj cai.
Cov txiaj ntsig
Qhov txiaj ntsig tseem ceeb ntawm doxorubicin hydrochloride yog nws qhov muaj zog thiab dav -spectrum anticancer kev ua haujlwm, uas tshwm sim los ntawm ntau lub tswv yim, suav nrog DNA intercalation, topoisomerase II inhibition, thiab tiam ntawm hom reactive uas cuam tshuam kev ua haujlwm ntawm tes. Nws multifaceted hom kev txiav txim ua rau nws zoo tiv thaiv sai sai faib cov qog nqaij hlav cancer thiab pab tau nyob rau hauv ntau hom qog nqaij hlav. Qhov sib xyaw ua ke muaj ntau xyoo ntawm kev siv tshuaj kho mob, muab nws qhov zoo - tus yam ntxwv profile uas tso cai rau cov kws kho mob thiab cov kws tshawb fawb kom nkag siab txog nws tus cwj pwm, kev sib raug zoo ntawm koob tshuaj, thiab kev sib koom ua ke hauv kev kho mob ua ke. Nws suav nrog hauv ntau cov txheej txheem kev tswj hwm pab ua tiav cov lus teb kho mob uas tuaj yeem ua rau qog nqaij hlav ntsws lossis kev tswj kab mob. Hauv kev tshawb fawb, nws qhov kev kwv yees cytotoxic profile ua rau nws muaj txiaj ntsig zoo rau kev ntsuas kev xa khoom tshiab, sensitizers, thiab cov tswv yim ua ke. Nws muaj dav dav thiab kev ua tau zoo ib yam txhawb nqa cov txiaj ntsig zoo hauv kev sim oncology.
Xaus
Doxorubicin hydrochloride yog ib qho tseem ceeb anthracycline compound siv dav hauv kev kho mob qog noj ntshav thiab kev tshawb fawb oncology. Nws muaj zog anticancer kev ua si, versatility nyob rau hauv ntau hom qog nqaij hlav, thiab muaj txiaj ntsig zoo raws li cov qauv sib xyaw hauv kev tshawb fawb txog kev tshawb fawb pom tau tias nws qhov tseem ceeb txuas ntxiv hauv kev kho mob thiab kev tshawb fawb ib puag ncig. Thaum nws txoj kev siv tshuaj kho mob yuav tsum tau ua tib zoo tswj xyuas vim muaj cov kev mob tshwm sim, nws lub luag haujlwm tsim thiab siv dav ua rau nws yog lub hauv paus rau kev txhawb nqa cov tswv yim kho mob qog noj ntshav thiab nkag siab cov lus teb ntawm tes rau kev ntxhov siab chemotherapeutic.
Cim npe nrov: Doxorubicin hydrochloride 丨cas 25316-40-9, Tuam Tshoj doxorubicin hydrochloride 丨cas 25316-40-9 manufacturers, lwm tus neeg, Hoobkas
