Cov lus qhia
|
Zog: |
Dawb rau off-dawb hmoov |
|
Melting taw tes: |
72-80 degree |
|
Qhov muag tig: |
{{0 {}} degree ~ +17 degree |
Daim qhia npe
|
Kev kuaj tus kheej ntawm UV: |
Spectral ntau: 200-400 nm; Kev nqus tau Max: 224 nm; Kev nqus kom tsis muaj zog: 277 nm |
|
Kev xeem cim ntawm HPLC: |
Kev muag khoom ntawm lub ncov loj yuav tsum phim cov qauv kev daws teeb meem |
|
Purity: |
99. {0}% min |
Lwm yam tshuaj
|
Isomer: |
{{0 {}}. 10% Max |
|
Unspecified impurities: |
{{0 {}}. 10% Max |
|
Tag nrho cov impurity: |
1. {0 max |
|
Feem pua ntawm Propanediol: |
13.6%–16.6% |
|
Dej: |
3.0%–4.4% |
|
Residue ntawm ignition: |
0. 1% Max |
|
Cov hlau hnyav: |
20 PPM Max |
Residual cov kuab tshuaj
|
Methanol: |
0. 3% Max |
|
Ethanhol: |
{{0 {}}. 5% Max |
|
Acetoniturile: |
{{0 {}}. 041% Max |
|
Dichhloromethane: |
{{0 {}}. 06% Max |
|
Ethyl acetate: |
{{0 {}}. 5% Max |
|
n-hexane: |
{{0 {}}. 029% Max |
|
Thf: |
{{0 {}}. 072% Max |
|
Toluene: |
{{0 {}. 089% Max |
|
Assay: |
98. {{0% - 1 {{}} 2.0% ntawm c21H25Clo6(anhydrous, tsis muaj propanediol) |
Cov Ntaub Ntawv Thauj
|
Chaw ua uas tsis tau haus |
Kev qhia tshwj xeeb |
|
UN NUM |
|
|
Hom |
|
|
Cov Pab Pawg |
|
|
Hs code |
2932999099304 |
|
Ruaj khov & rov ua |
Cov khoom lag luam ruaj khov nyob rau hauv cov qauv ambient ambient. |
|
Chaw ntim khoom |
Nruj nreem kaw. Khaws rau hauv qhov chaw kaw, qhuav, qhov chaw cua |
|
Mob kom tsis txhob |
Muaj zog oxidizing cov neeg sawv cev |
|
Lub thawv |
Cov ntaub ntawv raug
|
Chaw ua uas tsis tau haus |
Kev qhia tshwj xeeb |
|
Lub peev xwm |
|
|
Hov ntau |
|
|
Lub teb chaws tseem ceeb |
|
|
Peev Xwm \/ Batch |
100kg |
|
Paub lawm |
Ntau lawm txij xyoo 2009 |
|
Ntxiv rau |
Hauv Tshuag |
Lub ntsiab
Dapagliflozin propanediol 丨 cas 960404-48-2yog aCov Sodium-Loos Co-Transporter 2 (SGLT2) Inhibitor, siv feem ntau hauvKev Kho Mob Hom 2 Ntshav Qab Zib MellitusCov. Nws yog tusPropanediol Dolvatentawm Dapagliflozin, uas txhim khoLub zog lub cev zoo li solubility thiab ruaj khovYog tsis muaj kev hloov pauv tshuaj ntawm lub chaw muag tshuaj. Dapagliflozin txo qis cov ntshav zoo siab theem los ntawm kev txhawb nqa cov piam thaj hauv cov zis.
Cov Ntawv Thov
1. Kev kho mob hom 2 Ntshav Qab Zib Mellitus
Thawj daim ntawv thovyog ua qhov ncauj tiv thaiv kab mob ntshav qab zib.
InhibitsSGLT2Nyob rau hauv lub proximal raum tubules,Txo rearotorption ntawm cov piam thajthiab txhawb nqaZis tsoos dej txaus ntshai.
Ua tau zoo liMonotherapyLos yog ua ke nrog lwm cov tshuaj xws li manformin, insulin, lossis dpp -4} inhibitors.
2. Lub plawv tsis ua haujlwm thiab kav ntev raum (CKD)
Dapagliflozin tau pom tias yuav txo qis kev pheej hmoo ntawmTuag plawvthiabKhummization rau lub plawv tsis ua hauj lwm, Txawm hais tias muaj ntshav qab zib li ntshav qab zib li.
PomLub raum tiv thaiv cov teebmeem, maj mam ua kom tiav ntawm cov kab mob raum.
Pom zoo rau kev siv hauvHFRF (Lub Plawv Tsis Ua Tsis Zoo nrog Kev Txo Kev Ntsuas Feem Ntsuam)thiab CKD cov neeg mob.
3. Qhov hnyav poob thiab ntshav siab
MuabNyuaj Siab Nyhavvim muaj caloric ploj ntawm glucosuria.
Kev ua yeeb yamCov teebmeem diuretic me me, pab qis duaSystolic thiab diatolic ntshav siab.
Cov txiaj ntsig
Zoo glucose kev txo qistsis muaj kev ua rau hypoglycemia (thaum siv ib leeg).
TxoKev pheej hmoo mob plawvthiab muabkev tiv thaiv raum.
Txhim khoglycemic tswj, AIDS hauvLub cev yuag, thiab pab nyob rau hauvNtshav Siab Tswj.
Zoo nyiamQhov ncauj Bioavailabilitythiab kev zam tau zoo nyob rau hauv kev siv ntev.
Lub ntsiab
Dapagliflozin propanediol 丨 cas 960404-48-2yog ib qho kev tsim txiaj ntawm Dapagliflozin siv los tswjMob Ntshav Qab Zib Hom 2, Lub plawv tsis ua hauj lwm, thiabChra Mob Mob Mob Mob Mob MobCov. Raws li ib tugSLGT2 INHIBITOR, nws txhim kho cov txiaj ntsig tus neeg mob los ntawm kev txo cov ntshav qab zib, ib qho kev txo phaus, thiab cov txiaj ntsig kev tiv thaiv thiab cov txiaj ntsig tsis txaus siab. Tus propanediol dolvate tsim kom muaj txiaj ntsigTxhim kho ruaj khov thiab bioavailability, ua rau nws xaiv xaiv qhov kev xaiv hauv chaw tshuaj.
Cim npe nrov: Dapagliflozin Propanediol 丨 Cas 960404-48-2}}}}}}, Tuam Tshoj Dapagliflozin Profile Cov Chaw Tsim Khoom, Chaw Tsim Tshuaj, Chaw Tsim Tshuaj
