Amifostine 丨 CAS 112901-68-5

Amifostine 丨 CAS 112901-68-5yog atawmTsim los tiv thaiv cov ntaub so ntswg qub los ntawm cov tshuaj lom ntawm kev siv tshuaj kho mob thiab hluav taws xob kho. Nws yog Ameslikas tsim los ntawm Walter Reed Army Institute ntawm kev tshawb fawb thiab tom qab ntawd ua lag luam los txo cov kev mob ntawm kev kho mob cancer.

Amifostine ua haujlwm los ntawm xaiv scavengingreactive oxygen hom (Ros)thiab detoxifying cov metabolites tsim los ntawm hluav taws xob lossis tshuaj kho mob, yog litiv thaiv cov hlwb ib txwm tsis txo qhov ua tau zoo ntawm kev kho mob cancer.

1. Kev tiv thaiv hluav taws xob

Amifostine 丨 cas 112901-68-5} yog fda-pom zoo los txohluav taws xob-induced xerostomia(Lub qhov ncauj qhuav) hauv cov neeg mob tawg kom zoo rau lub taub hau thiab caj dab cancer.

Tiv thaivCov qog ua qoglos ntawm hluav taws xob puas tsuaj

Txo cov tsos mob xws liQhov ncauj qhuav, nyuaj nqos, thiabQhov ncauj ntawm lub qhov ncauj

Txhim kho tus neeg mobLub neej zooThaum lub sij hawm thiab tom qab hluav taws xob kho hluav taws xob

2. Kev txo nqi tshuaj lom rau kev txo qis

Siv los txoCisplatin-indce neprotoxicity(raum kev puas tsuaj):

Cisplatin yog cov tshuaj siv tshuaj kho mob tab sis tuaj yeem ua rau lub plab lom neeg lom zem.

Amifostine tiv thaiv lub raum tubular tsaj los ntawm kev ua phem platfed platural metabolites metabolites.

Ua rau cov khoom siab dua lossis ntau dua cisplatin dosing nrog tsawg dua kev phiv.

Tsis tas li ntawd, amifostine yuav txo qis kev lom los ntawm lwm cov neeg sawv cev alkylating thiab platinum-raws li cov tshuaj.

3. Cov pob txha tiv thaiv

Amifostine muab qeemeloproterrotective cuam tshuam, txo pob txha pob txha los ntawm kev siv tshuaj kho mob, tso cai rau tus neeg mob kom zoo rau kev kho.

4. Kev ua haujlwm thiab tshawb fawb

Kawm txogKev tiv thaiv tiv thaiv hluav taws xob raugHauv cov chaw tsis-cancer (piv txwv li hluav taws xob tawg lossis chaw sib tua)

Tshawb xyuas hauv kev kho kom haum rauTxo cov tshuaj lom ntawm lwm cov neeg sawv cev anticancer

Tej zaum cov haujlwm neuroprotreective hauvNeurodegenerative Kab Moblossistxoj hlab ntsha

1. Kev xaiv cytoprotection

Tiv thaiv cov ntaub so ntswg uas tsis cuam tshuam nrog qog cond tua, vim muaj kev xaiv ua kom zoo nkauj.

Minimizes kev cuam tshuam zoo, txhim khoPatience Adherence Thiab Kev nplij siab.

2. Txhim Kho Qhov Ntsuas Hluav Taws Xob

Tso caiCov koob tshuaj ntau dua los yog siv cov sijhawm khontawm hluav taws xob thiab cov tshuaj kho mob los ntawm kev txo cov tshuaj lom neeg lom zem.

Tuaj yeem txhim khoKev Kho Kom Tautsis ncaj qha los ntawm kev txhim kho kev kho hnyav dua.

3. Zoo ntawm kev txhim kho lub neej

Txo kev cuam tshuam debilitating xws liQhov ncauj qhuav, uas cuam tshuam rau kev hais lus, saj, thiab kev tu cev ntawm qhov ncauj.

Tiv thaiv cov raum thiab pob txha pob txha, txo kev pab pw hauv tsev kho mob thiab cov kev xav tau kev pab txhawb nqa.

Amifostine 丨 CAS 112901-68-5yog ib qho tseem ceebTus Neeg Sawv Cev CyToprotiveSiv feem ntau rau:

Ua kom me duaHluav taws xob hluav taws xob-ua kom puas tsuajnyob rau hauv cov ntaub so ntswg ib txwm, tshwj xeeb tshaj yog cov qog

Tiv thaivKev siv tshuaj kho mob-induced neprotoxicity, tshwj xeeb yog cisplatin

Minimize pob txha nyom toxicity

NwsCov Kev Xaiv TsaHauv cov hlwb ib txwm tso cai rau kev siv tus mob cancer kev siv kabmob cancer tsis muaj peev xwm cuam tshuam tsis tau kev ua tau zoo. Amifostine tau cuam tshuam ntau dua covLub neej zooRau cov neeg mob tab sis cancer kev kho mob qog noj ntshav thiab txhawb nqa cov dosing regomens.