Tributylsilane 丨 CAS 998-41-4

1. Hydrogen Atom pub dawb intomator

Tributylsilane yog qhov txiaj ntsig hydrogen zoo nyob rau hauv cov tshuaj tiv thaiv nruab nrab, uas nws tau daws cov kab mob hydrogen rau cov kev txiav tawm lossis txo cov hom sib txawv. Cov ntawv thov raug muaj xws li:

RADICAL DEHALOGENATION (tshem tawm ntawm ntau ntawm Alkyl lossis Aryl Halides)

Txo cov tshuaj tiv thaiv kab mob O-N thiab N-N-N-n los tiv thaiv pab pawg

Cov Kev Xaiv Tin-dawb dawb rau Tributyltin Hydride (Bu₃snh) hauv kev tawm tsam tshaj plaws vim muaj kev lom zem tsawg

Qhov Zoo:

MHDER thiab muaj kev nyab xeeb dua li kev txiav txim siab

Tau tshaj yog ntau ntawm cov kuab tshuaj thiab substrates

Cov ntaub ntawv tsis muaj tshuaj lom (cov siloxanes lossis silanols)

2. Reductive deprotection are

Kev Pab Cuam Tshoj Feem ntau siv rau kev tshem tawm ntawm cov pab pawg tiv thaiv, tshwj xeeb tshaj yog cov lus qhia thaum lub sij hawm peptide synthisical lossis carbohydrate chemistry. Cov kev tawm dag zog tsis muaj kev cuam tshuam nrog:

Cleavage ntawm Benzyl lossis BenzyloxCarbonyl (CBZ) Pawg

Desulfurization ntawm thiols thiab thioethers

Txo ntawm sulfoxides thiab n-oxides

Siv ua ke nrog Lewis acids (piv txwv li, tfa lossis bfautlamo), kev txiav txim

3. Hydrosilylation tshua muaj

Raws li hydrosilane, Tributylsilane tuaj yeem ua rau hi hydrosilylation, ntxiv cov pa roj carbon-carbon lossis carbon-heteroatom khi:

Ntxiv rau alkenes lossis alkynes los ua alkyl- lossis vinylsilanes

Catalyzed los ntawm kev hloov pauv ntawm cov hlau (piv txwv li, pt, rh, lossis pd)

Qhov no muaj txiaj ntsig rau synthesizing organosilicon tebchaw nrog cov khoom ntiag tug rau cov ntaub ntawv, txheej txheem, thiab khoom siv hluav taws xob.

4. Reagent hauv cov tshuaj sapticaltical

Tributylsilane tau ua haujlwm hauv ntau yam khoom xyaw ua haujlwm (API) cov kauj ruam, tshwj xeeb hauv:

Peptide Coupling kev tawm tsam, uas nws pab tshem tawm cov pab pawg tiv thaiv lossis cov khoom lag luam sab

Kev ua yeeb yam synthesis, ua kom yooj yim tsis muaj kev cuam tshuam rau cov pab pawg ua haujlwm rhiab

Macrocyclization lossis cov theem pib yuav tsum yuav tsum tau txo me me

5. Silyl qhov chaw nyob hauv qhov kev txwv

Txawm hais tias tsawg dua li lwm cov neeg sib txuas, Tributylsilane tuaj yeem siv rau hauv kev hloov kho saum npoo lossis ua tus ua ntej rau cov khoom simicon. Nws qhia txog hydrophobic alkylsilicon qhov chaw uas txhim kho:

Ya raws tsis kam

Nto Zog Tswj rau hauv Txheej Txheej thiab Films

Compatibility nrog cov organic polymers

✅ Tin-Dawb radical Chemistry

Txoj kev nyab xeeb rau cov orgototin hydrides, uas yog cov tshuaj lom thiab ib puag ncig tas li.

Tributylsilane zam tin tsis huv hauv cov tshuaj lossis zoo tshuaj synthesis.

✅ Meej me thiab xaiv kev txo qis

Txuag hydrogen pub hauv acid-rhiab lwg me me

Tau tshaj Lewis thiab Brønsted cov kua qaub (piv txwv li, tfa, bf₃, alcl₃)

Cov Pab Pawg Ua Haujlwm Pab Pawg Ua Haujlwm: Tso cai, Ketones, yog neeg paub, thiab cov chaw nyob

✅ qes tsawg thiab yooj yim tuav

Piv rau tin hydrides, Tributylsilane muaj kev nyab xeeb zoo dua thiab ib puag ncig profile.

Tsis tshua muaj kev hloov pauv thiab tswj cov ntxhiab ua rau nws siv tau yooj yim rau siv hauv kev kuaj lossis sim cov txheej txheem.

Siv tau rau ib qho kev dav dav ntawm substrates

Ua haujlwm nrog alkyl, aryl, alkenyl, thiab heteroaromatic tshuab

Siv nyob rau hauv cov khoom muaj cov khoom zoo nkauj ua hluavtaws, cov tshuaj tua tshuaj, thiab agnemical kev loj hlob