CBZO 丨 CAS 1199616-66-4

1. Tshawb nrhiav

Cbzo yog qhov tseem ceeb hauv nruab nrab hauv cov hluavtaws ntawm cov tshuaj tua kab mob, anticancer, thiab cov neeg tuaj yeem tshuaj tiv thaiv yeeb tshuaj.

Triazole-muaj sib txuas xws li CBZO yog biopososes ntawm cov chaw nkaum thiab lwm yam kws tshuaj, ua rau lawv muaj txiaj ntsig zoo rau kev kho cov tshuaj zoo li kev hloov kho.

2. Tshuaj ntsuab Chemistry Scaffold

Qhov 1,2,3-triazole moamior yog paub zoo rau nws cov kev ruaj khov metabolic, cov muaj peev xwm ua tau zoo nkauj, thiab ua kom zoo dua qub.

CBZO feem ntau siv nyob rau hauv kev tsim ntawm Kinease inhibitors, enzyme blockers, thiab protein ntau yam kev cuam tshuam.

3. Tshuaj Lom Zem Nruab Nrab Nruab Nrab

Ua raws li lub tsev thaiv uas muaj hluav taws xob ntawm Heterocyclic tebchaw, tshwj xeeb yog cov kab mob pathogenic lossis cov qog nqaij hlav cancer.

Pab tau nyob rau hauv Nyem Chemistry, tshwj xeeb yog CUAAC (tooj liab (i) -catalyzed azide-alkyne cycloition) cov tswv yim rau lub tsev qiv ntawv ceev.

4. Agochnical kev tshawb fawb

Triazole-muaj cov carboxylic acids zoo li CBZO tuaj yeem pab cov qauv coj lossis nruab nrab hauv kev txhim kho cov fungicides lossis cov nroj tsuag kev cai tswj hwm.

✅ biologically tus qauv tsim nyog

Lub nplhaib triazole tau raug lees paub rau nws cov dav-spectrum bioactivity, tsawg toxicity, thiab zoo tshaj phathaoninetics.

✅ Tshuaj Muaj Peev Xwm

CBZO yog siv tshuaj khov kho nyob rau hauv ntau yam kev mob, cia nws siv rau ntau kauj ruam synthesis.

✅ Versetity ntau yam

Cov carboxylic acid pab pawg enables yooj yim conjugation, thiab kev siv nyiaj es, ua CBZO tsim kom muaj kev lom zem sib piv.

Pab tswj cov tshuaj kho kom zoo

Raws li kev ua haujlwm triazole, CBZo muab cov chaw rau SAR (qauv-kev sib raug zoo) kev kawm, txhim kho cov neeg siv tshuaj uas muaj kev sib tw ntawm cov ntaub ntawv.