(S)-(-)-2,2-Bis(diphenylphosphino)-1,1-binaphthyl丨CAS 76189-56-5

(S) - ({}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}} binap, yog chairos diphosphine lig siv nyob rau asymmetric catalysis thiab epentsometallic Chemistry. Nws cov ntawv thov tseem ceeb yog nyob rau hauv kev hloov pauv-hlau-catalyzed asymmetrication, xws li nws sib txuas, qhov twg nws ua kom muaj kev xaiv cov khoom sib txuas. Nws yog qhov ua tau haujlwm ntau hauv cov tshuaj thiab zoo tshuaj lom neeg ua haujlwm los tsim cov khoom noj kom huv si, cov khoom xyaw ua haujlwm, thiab agnaphicals. Lub nruj, axially chiral binap lub cev ntas muab cov chaw sib luag thiab cov hluav taws xob ib puag ncig lub hlau nruab ntug, txhim kho ob qho tib si cuam tshuam thiab enantioselectivity. Ib qho ntxiv, nws yog siv rau hauv kev ua kev tsim cov kws ua haujlwm rau kev tsim cov chairal hlau ua ke nrog cov khoom catalysic.

Cov txiaj ntsig ntawm (s)-}}} chiral binaphbth caj qaum thiab hluav taws xob {1} richyre nplua nuj diphenylphino cov pab pawg. Lub cev ntas yeej tso cai rau kev tswj hwm kev sib txawv ntawm cov txheej txheem sib txawv ntawm cov hlau chaw, ua rau muaj kev cuam tshuam siab hauv cov tshuaj asymmetric. Nws txoj kev sib haum xeeb rau kev hloov pauv ntawm kev hloov pauv ntawm kev hloov kho catalytic ruaj khov thiab kev ua si, ua rau muaj kev tshwm sim me me. Lub Ligand cov versatility tso cai rau nws los tsim cov nyom nrog ntau yam ntawm cov hlau xws li Ruthenium, thiab palladium, nthuav tawm nws txoj haujlwm thoob plaws kev hloov pauv Asymmetric. Nws siv hauv tshuaj thiab zoo tshuaj lom neeg synthesis ua kom yooj yim ntawm cov tshuab ntshiab ntshiab, txo qhov kev xav tau rau cov txheej txheem downstream thiab txhim kho tag nrho cov txheej txheem kev ua haujlwm.