Cov lus qhia
| Zog: | Dawb khoom |
| Purity (GC): | 98% min |
| Nws noo: | 0.5% max |
| 1.5% Max |
Cov Ntawv Thov
1. Tshuaj Nruab Nrab
Feem ntau siv los ua lub tsev thaiv nyob hauv synthesis ntawm cov khoom xyaw tshuaj muaj zog (APIs) thiab cov neeg sib tw tshuaj.
The presence of the fluoro and bromo substituents provides key reactive sites for cross-coupling reactions (eg, Suzuki, Buchwald-Hartwig), allowing for diverse structural modifications.
Pab tau nyob rau hauv kev tsim aryl-hloov heterocycles, uas tau nthuav dav nyob rau hauv ntau cov tshuaj scaffold (piv txwv, tshuaj tiv thaiv mob cancer, anti-inflampatory, cns tshuaj).
2. Agochnical synthesis
Ua hauj lwm ua qhov tseem ceeb hauv synthesation, fungicides, thiab cov tshuaj tua kab, ob qho tib si hauv cov molecules hauv agochemicals.
3. Cov Khoom Taw Qhia
Siv nyob rau hauv cov synthesis ntawm kev ua haujlwm aromatic tebchaw rau cov ntaub ntawv siab xws li:
Ua kua muaju
Txha hniav
Cov Neeg Tshwj Xeeb Polymers
Nws lub tshuab hluav taws xob-rho tawm nitrile thiab halogen atoms cuam tshuam hluav taws xob cov khoom ntawm cov khoom muaj ntxhiab ntawm cov ntxhiab.
4. Txuj Ci Kev Tshawb Fawb
Ib qho txiaj ntsig zoo halogenated cov muaj txiaj ntsig precutic hauv cov xwm txheej hauv Suav rau:
Nucleophilic Aromatic Hloov (SNAR)
Palladium-catalyzed coupling kev tawm tsam
Cyanation lossis derivatization ntawm Nitrile txoj hauj lwm
Cov txiaj ntsig
1. Multi-Functional Rev Mob
Fluoro thiab bromo pawg muab orthogonal reactivity:
Bromine yog amenable rau hlau-catalyzed hla-txuas (piv txwv li, Suzuki, Heck, Sonogashira).
Fluorine txhim kho Lipoplophilicity thiab metabolic ruaj khov hauv cov tshuaj sib txuas.
Nitrile Group muaj cov hauv kev rau kev hloov pauv ntxiv, suav nrog kev ua si, hydrolysis, lossis txo qis.
2. Cov Lus Qhia Txog Cov Qauv
Ua txhaum ua ib qho kev ua haujlwm hauv nruab nrab rau cov qauv tsim muaj sib txawv, tseem ceeb hauv cov tshuaj chemical thiab kev txhim kho tshuaj lom neeg.
3. Kev ruaj khov thiab kov
Solid-state stability makes it suitable for long-term storage and transportation.
Yooj yim los tuav hauv cov txheej txheem organic synthesis workflows.
4. Txhim kho cov peev txheej bioactivity
Halogen thiab Nitrile hloov chaw yog ob qho tib si paub los cuam tshuam:
Binding affinity hauv cov hom phiaj biological
Xaiv thiab Bioavailability
Electron faib tawm hauv cov rings alomatic
Tag
5-Bromo-2-fluorobenzonitrile (CAS 179897-89-3) Yog ib qho muaj ntxhiab tsw qab los ua cov ntawv thov kev tshawb fawb ntau, agnochemical, thiab cov khoom siv tshuaj ntsuam kev tshawb fawb. Nws muaj kev sib xyaw ntawm cov chaw ua si-fluorine, bromine, thiab nitrile-enables ua haujlwm ntau yam sib txawv hauv cov khoom siv hluav taws xob hauv niaj hnub no.
Cim npe nrov: 5-Bromo-2-fluorobenzonitrile 丨 CAS CAS CAS CAS CAS TIB 179897-8-Bromo-2-Fluorobenzonitrile E CAS li 179897-829-3 Cov Chaw Tsim Tshuaj, Chaw Tsim Tshuaj
