(2-bromo-6-fluorophenyl) boronic acid 丨 CAS yog 913835-80-0

Lub ntsiab

(2-bromo-6-fluorophenyl) boronic acid 丨 CAS yog 913835-80-0yog aHalogenated Arylbboronic acid, feem ntau siv raws li aSynthetic Nruab Nrabhauv cov organic thiab tshuaj chemistry. Nrog ob qho tib sibroorinethiabcov tshuaj fluorinecov chaw nyob ntawm lub nplhaib muaj ntxhiab, nws muaj kev cuam tshuam tshwj xeeb rauHla kev sib txuas, tshwj xeebSuzuki-Miyaura Coupling.

Cov Ntawv Thov

1. Suzuki-Miyaura Cross-Coupling Regions

Thawj sivhauvpalladium-catalyzed suzuki cov kev cuam tshuamnrog aryl haldides lossis triflates los uaBiEL cov tebchaw.

Lub xub ntiag ntawmbromine thiab fluorinetso cai zoo-tuning ntawmHauv cov teebmeemthiabregioselectivity.

Thov nyob rau hauv synthesis ntawmKws Tshuaj, agnchemicals, thiabCov ntaub ntawv hluav taws xob.

2. Kws Tshuaj Nruab Nrab

Siv raws li aLub Tsev ThaivHauv synthesis ntawmhetercycles, Aryl Amines, thiabCov khoom xyaw tshuaj (APIs).

Cov kua qaub feem ntau yog qhov tseem ceeb hauv kev tsimprotaslivE inhibitorsthiab lwm yambiologically nquag molecules.

3. Agnemical kev loj hlob

Ua hauj lwm hauv kev tsimfluorinated agnochemical cov neeg sib tw, qhov twgfluorine hloovtuaj yeem nce ntxivmetabolic ruaj khovthiabbioactivity.

4. Cov Khoom Taw Qhia

Siv nyob rau hauv synthesis ntawmTxha hniav, Organic semiconductors, thiabCov Ntaub Ntawv Diamuam.

Lub halogenated aryl qauv enables ua kom haumCov Khoom Siv Hluav Taws Xobnyob rau hauv conjugated systems.

5. Boron-muaj cov ligands lossis sensors

Tej zaum yuav yog aprefursor rau kev ua haujlwm boron raws moleculesnyob rau hauv sensors, catalysts, lossis supramolecular moj khaum.

Cov txiaj ntsig

1. Dual hloov chaw: fluorine thiab bromine

Cov tshuaj fluorinentuasLipophilicity, metabolic tsis kam, thiabElectron-rho tawm cov yam ntxwv, txhim kho kev ua haujlwm roj ntsha.

Broorinetso cai ntxivKhoom siv hluav taws xob yooj yim-Txoj kev khaws cia lossis siv hauv kev hloov pauv ntxiv (piv txwv li, Sonogashira, Heck txuas ntxiv).

2. Versatile boronic acid moiete

Pawg acid yogHigh reactiveHauv Suzuki Coupling thiabyooj yim hloovmus rau hauv cawv, esters, lossis chaw nyob.

PubKev Tshaj Tawmnrog pab pawg ua haujlwm nyob rau hauv cov mob me.

3. Kev pab kho

Cov qauv sib xyaw ua qauv zoo tagnrho rauTus qauv-kev sib raug zoo (SAR) kev tshawb fawb, tshwj xeeb tshaj yog cov tshuaj chemical, qhov twg hloov halogen txoj haujlwm tuaj yeem cuam tshuam ntau yam kev ua si.

4. Ua txuj ci siab ua hauj lwm zoo

Cov cim hloov txawv txawv enablesXaiv cov khaub lig-txuas, ua rau nws haum rau lub tsevcomplex molecular scaffolds.

Lub ntsiab

(2-bromo-6-fluorophenyl) boronic acid 丨 CAS yog 913835-80-0yog ib qho txiaj ntsig halogenated arylbbi acid feem ntau siv hauvSuzuki-Miyaura Cross-Coupling RegionsCov. Nws cov halogen hloov chaw muajKhoom siv hluav taws xob yooj yimthiabTxhim Kho Cov Khoom Hluav Taws Xob, ua rau nws txaus nyiam heev hauvKws muag tshuaj, agnikemical, thiab cov khoom siv tshuaj ntsuam.