Hangzhou Leap Chem Co., Ltd. yog ib qho ntawm cov kws tshaj lij thiab cov neeg muag khoom ntawm ethynyl estradiol丨cas 57-63-6 hauv Suav teb. Txais tos rau kev lag luam wholesale kev cai ua cov khoom lag luam ntawm tus nqi sib tw los ntawm peb lub hoobkas. Rau cov khoom pheej yig dua, tiv tauj peb tam sim no.
Specifications
| Qib | USP36 |
| Yam ntxwv | Dawb rau creamy dawb, tsw tsw, crystalline hmoov |
| Cov ntsiab lus | 97.0 ~ 102.0% |
| TLC | Qhov zoo |
| UV spectrum | Qhov zoo |
| IR spectrum | Qhov zoo |
| Solubility | Soluble hauv cawv, chloroform, ether, zaub roj, thiab kev daws teeb meem ntawm alkali hydroxides ruaj khov; insoluble hauv dej |
| Kev ua tiav ntawm kev daws teeb meem | Dissolve 100 mg hauv 5 mL cawv; cov tshuaj yog ntshiab thiab dawb los ntawm undissolved khoom |
| Melting point | 180-186 degree |
| Kev sib hloov kho qhov muag tshwj xeeb | -28 ° ~ -29.5 ° C |
| Poob rau ziab | 1.0% max |
| Residual kuab tshuaj - Acetone | Tsawg dua lossis sib npaug li 5000 ppm |
Daim ntawv thov
Ethynyl estradiol yog cov tshuaj estrogen hluavtaws dav siv hauv kev siv tshuaj thiab kev kho mob, feem ntau hauv kev kho hormonal. Nws yog ib qho tseem ceeb active ingredient nyob rau hauv ua ke lub qhov ncauj contraceptives, tshuaj hormone replacement therapy (HRT), thiab kev kho mob rau cov poj niam cev xeeb tub, endometriosis, thiab estrogen deficiency. Hauv kev tshawb fawb tshuaj, ethynyl estradiol yog ua haujlwm los ua cov ntaub ntawv siv los kawm txog cov tshuaj estrogen receptor binding, metabolism, thiab pharmacokinetics. Nws kuj tseem siv rau hauv kev tsim cov tshuaj estrogenic tshiab lossis xaiv cov tshuaj estrogen receptor modulator (SERM) derivatives rau kev kho mob. Tsis tas li ntawd, qhov sib xyaw pom cov ntawv thov hauv kev tshawb fawb endocrinology los tshawb xyuas cov kev cai hormonal, kev ua me nyuam biology, thiab cov teebmeem ntawm estrogens ntawm ntau lub cev lub cev.
Cov txiaj ntsig
Ethynyl estradiol muaj ntau yam zoo vim nws qhov ncauj bioavailability, metabolic stability, thiab muaj zog estrogenic kev ua si. Cov pab pawg ethynyl ntawm C17 txoj haujlwm txhim kho kev tiv thaiv kab mob siab metabolism, ua rau muaj txiaj ntsig zoo los ntawm kev tswj hwm qhov ncauj. Cov cuab yeej no tso cai rau kev txhaj tshuaj meej, ua haujlwm zoo ib yam, thiab kev kho mob ntev. Nws muab cov kev cai txhim khu kev qha ntawm kev coj khaub ncaws, kev tiv thaiv zoo, thiab txo cov tsos mob estrogen deficiency nrog rau qhov zoo- yam ntxwv kev nyab xeeb profile. Hauv cov ntawv thov kev tshawb fawb, nws cov receptors uas tuaj yeem ua tau- khi cov khoom thiab tshuaj lom neeg ruaj khov ua rau nws muaj kev cia siab rau kev kawm txog kev ua estrogenic thiab tsim kho tshiab.
Xaus
Ethynyl estradiol yog ib qho tseem ceeb ntawm cov tshuaj estrogen nrog kev siv dav hauv kev tiv thaiv kab mob, kev kho tshuaj hormone, thiab kev tshawb fawb tshuaj. Nws cov txiaj ntsig, suav nrog kev ua haujlwm muaj zog, qhov ncauj bioavailability, metabolic stability, thiab kev ntseeg siab hauv cov kev tshawb fawb estrogen receptor, ua rau nws yog ib qho tseem ceeb hauv kev kho mob thiab kev tshawb fawb. Cov tshuaj txuas ntxiv txhawb kev nce qib hauv kev noj qab haus huv ntawm cov menyuam yaus, kev kho mob endocrine, thiab kev txhim kho cov tshuaj estrogen tshiab- txog kev kho mob.
Cim npe nrov: Tuam Tshoj ethynyl estradiol 丨cas 57-63-6 manufacturers, lwm tus neeg, Hoobkas
