(2S)-1-(1R)-1-(Dimethylamino)ethyl-2-(diphenylphosphino)ferrocene CAS 74311-54-9

(2S)-1-(1R)-1-(Dimethylamino)ethyl-2-(diphenylphosphino)ferrocene yog ib qhochiral ferrocene-raws li phosphine liganddav siv hauv asymmetric catalysis thiab organometallic chemistry. Nws qhov tshwj xeeb ua ke ntawm cov pob txha ferrocene, phosphine moiety, thiab chiral dimethylaminoethyl hloov pauv tso cai rau tsim cov enantioselective hlau complexes nrog palladium, rhodium, ruthenium, thiab lwm yam hlau hloov. Cov hlau-ligand complexes yog siv nyob rau hauv asymmetric hydrogenation, allylic hloov, hydroformylation, thiab cross-coupling tshua, uas yog ib qho tseem ceeb nyob rau hauv lub synthesis ntawm enantiomerically ntshiab tshuaj, zoo tshuaj, thiab agrochemicals. Lub compound kuj tseem siv rau hauv kev tshawb fawb los tsim cov chiral catalysts tshiab, kawm cov tshuaj tiv thaiv mechanisms, thiab optimizing catalytic efficiency thiab selectivity. Nws ferrocene scaffold imparts rigidity thiab stability rau lub ligand, txhim khu kev ua tau zoo raws li xav tau cov tshuaj tiv thaiv.

Lub compound muaj ntau yam zoo vim nwstxhav ferrocene txha nraub qaum, chiral ib puag ncig, thiab muaj peev xwm sib koom ua ke ntau yam. Cov stereochemically txhais dimethylaminoethyl pawg muab enantioselectivity zoo heev, thaum lub diphenylphosphino moiety ua kom muaj zog thiab ruaj khov kev sib koom tes rau kev hloov hlau. Cov tub ntxhais ferrocene pab txhawb kev thermal thiab tshuaj lom neeg ruaj khov, tswj kev ua haujlwm catalyst txawm nyob rau hauv cov xwm txheej hnyav. Nws cov khoom siv hluav taws xob tunable thiab steric tso cai rau kev tswj xyuas cov txiaj ntsig zoo, suav nrog cov txiaj ntsig, kev xaiv, thiab stereochemistry. Cov ligand yog soluble nyob rau hauv cov organic solvents thiab muaj peev xwm ua tau zoo nyob rau hauv ntau yam hlau complexes, muab reproducible thiab siab -kev ua tau zoo rau ob qho tib si kuaj-scale thiab industrial asymmetric synthesis.